Chauhan Nidhi, Padhy Susanta Kumar, Shah Ruchita, Malhotra Savita
Department of Psychiatry, Government Medical College and Hospital, Chandigarh, India.
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Neurosci Rural Pract. 2019 Jan-Mar;10(1):16-20. doi: 10.4103/jnrp.jnrp_169_18.
Vitamin D is increasingly recognized as important for brain health, apart from its role in endocrine and bone health. There is a growing recognition of worldwide "epidemic" of Vitamin D deficiency, and growing data from adult population illustrate the association between Vitamin D deficiency and psychiatric disorders. In children, its role is implicated in brain development, function, and psychiatric disorders.
The aim of this study was to study the extent of Vitamin D deficiency in children and adolescents with psychiatric disorders.
Retrospective chart review of participants, who had attended the psychiatry outpatient department, was conducted to ascertain the extent of blood Vitamin D level requisition and its level.
Out of 836, 60 participants had received the requisition for blood Vitamin D level, and results were documented for 40 participants (males - 28; females - 12). No specific reason was cited for getting Vitamin D level done. The mean Vitamin D level was in the deficient range, i.e. 13.34 ng/ml with 80% of the sample having Vitamin D deficiency and 13% having insufficient Vitamin D level. More males had Vitamin D deficiency, however, the small number of females in the study limits the generalizability of the results. Among the diagnostic categories, neurodevelopmental disorders had lower mean Vitamin D level, with lowest Vitamin D for autism, i.e., 10.9 ng/ml.
The cause-effect relationship between Vitamin D deficiency and childhood psychiatric disorders could not be derived from the study. However, it provides important initial data for the relationship between Vitamin D deficiency and childhood psychiatric disorders from India.
维生素D除了在内分泌和骨骼健康方面发挥作用外，其对大脑健康的重要性也日益得到认可。全球范围内维生素D缺乏的“流行”现象日益受到关注，来自成年人群的越来越多的数据表明维生素D缺乏与精神障碍之间存在关联。在儿童中，其作用涉及大脑发育、功能及精神障碍。
本研究旨在探讨患有精神障碍的儿童和青少年中维生素D缺乏的程度。
对曾到精神科门诊就诊的参与者进行回顾性病历审查，以确定血液维生素D水平检测申请情况及其水平。
在836名参与者中，60人申请了血液维生素D水平检测，40人的检测结果有记录（男性28人；女性12人）。进行维生素D水平检测未提及具体原因。维生素D平均水平处于缺乏范围，即13.34纳克/毫升，80%的样本存在维生素D缺乏，13%的样本维生素D水平不足。男性维生素D缺乏者更多，然而，研究中女性数量较少限制了结果的普遍性。在诊断类别中，神经发育障碍患者的平均维生素D水平较低，自闭症患者的维生素D水平最低，为10.9纳克/毫升。
本研究无法得出维生素D缺乏与儿童精神障碍之间的因果关系。然而，它为印度维生素D缺乏与儿童精神障碍之间的关系提供了重要的初步数据。
