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严重酒精戒断和肝硬化中的尖端扭转型室速：对风险分层和管理的启示

Torsades de Pointes in Severe Alcohol Withdrawal and Cirrhosis: Implications for Risk Stratification and Management.

作者信息

Yamamoto Ted, Friedman Scott E

机构信息

is an internal medicine physician at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire. is a physician at White River Junction VAMC in Vermont and an assistant professor at Geisel School of Medicine in Hanover, New Hampshire.

出版信息

Fed Pract. 2017 Jan;34(1):38-41.

PMID:30766231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6372036/
Abstract

Close monitoring of the QT interval, timely and aggressive management of withdrawal, repletion of electrolytes, and telemetry monitoring may prevent life-threatening arrhythmias for patients being treated for acute alcohol withdrawal.

摘要

密切监测QT间期、及时且积极地处理戒断反应、补充电解质以及进行遥测监测，可能会预防正在接受急性酒精戒断治疗的患者发生危及生命的心律失常。

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Torsades de Pointes in Severe Alcohol Withdrawal and Cirrhosis: Implications for Risk Stratification and Management.严重酒精戒断和肝硬化中的尖端扭转型室速：对风险分层和管理的启示
Fed Pract. 2017 Jan;34(1):38-41.
2
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Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma.在一例肝硬化和肝细胞癌患者中与特非那定相关的尖端扭转型室速。
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Torsades de Pointes.尖端扭转型室性心动过速
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QT prolongation and Torsades de Pointes in patients previously treated with anthracyclines.曾接受蒽环类药物治疗的患者出现QT间期延长和尖端扭转型室速。
Anticancer Drugs. 2007 Apr;18(4):493-8. doi: 10.1097/CAD.0b013e328012d023.
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本文引用的文献

1
Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone.静脉注射胺碘酮后发生尖端扭转型室速和持续性QTc间期延长
Case Rep Med. 2012;2012:673019. doi: 10.1155/2012/673019. Epub 2012 Mar 5.
2
QT interval prolongation in liver cirrhosis: innocent bystander or serious threat?肝硬化患者的 QT 间期延长：无辜的旁观者还是严重的威胁？
Expert Rev Gastroenterol Hepatol. 2012 Feb;6(1):57-66. doi: 10.1586/egh.11.86.
3
Cirrhotic cardiomyopathy.肝硬化性心肌病。
J Am Coll Cardiol. 2010 Aug 10;56(7):539-49. doi: 10.1016/j.jacc.2009.12.075.
4
ECG changes amongst patients with alcohol withdrawal seizures and delirium tremens.酒精戒断性癫痫发作和震颤谵妄患者的心电图变化。
Swiss Med Wkly. 2006 Apr 1;136(13-14):223-7. doi: 10.4414/smw.2006.11319.
5
Prolongation of QTc interval: relationship with etiology and severity of liver disease, mortality and liver transplantation.QTc间期延长：与肝脏疾病的病因、严重程度、死亡率及肝移植的关系
Liver Int. 2003 Aug;23(4):243-8. doi: 10.1034/j.1600-0676.2003.00833.x.
6
Q-T interval prolongation in cirrhosis: prevalence, relationship with severity, and etiology of the disease and possible pathogenetic factors.肝硬化患者的QT间期延长：患病率、与疾病严重程度的关系、病因及可能的发病机制
Hepatology. 1998 Jan;27(1):28-34. doi: 10.1002/hep.510270106.
7
Prolongation of the QTc interval during alcohol withdrawal syndrome.酒精戒断综合征期间QTc间期延长。
Acta Cardiol. 1997;52(3):285-94.
8
Influence of increased adrenergic activity and magnesium depletion on cardiac rhythm in alcohol withdrawal.肾上腺素能活性增加和镁缺乏对酒精戒断时心脏节律的影响。
Br Heart J. 1994 Dec;72(6):554-60. doi: 10.1136/hrt.72.6.554.
9
Torsade de pointes complicating the treatment of bleeding esophageal varices: association with neuroleptics, vasopressin, and electrolyte imbalance.尖端扭转型室速使食管静脉曲张破裂出血的治疗复杂化：与抗精神病药物、血管加压素及电解质失衡的关联。
Am J Gastroenterol. 1995 May;90(5):822-4.
10
[Renal secretion of magnesium and other electrolytes under the influence of acute ingestion of alcohol, in normal subjects].[正常受试者急性摄入酒精对镁及其他电解质肾分泌的影响]
Rev Med Chil. 1968 Mar;96(3):138-41.