Wańczyk-Baszak Jadwiga, Woźniak Sławomir, Milejski Bartosz, Paszkowski Tomasz
3 Chair and Department of Gynaecology, Medical University of Lublin, Lublin, Poland.
Krapkowice Health Center, Krapkowice, Poland.
Prz Menopauzalny. 2018 Dec;17(4):180-184. doi: 10.5114/pm.2018.81743. Epub 2018 Dec 31.
Perimenopausal changes caused by oestrogen deficiency are accompanied by a decrease in the content of collagen and elastin in the tissues, leading to thinning of the epithelium and the resultant disappearance of the superficial layer, which leads to smooth muscle dysfunction as well as connective tissue degradation. This aetiopathogenetic chain results in a set of symptoms experienced by approximately 50% of women in the peri- and postmenopausal period. Symptoms of dryness, burning, dyspareunia and urgency contribute to a significant reduction in the quality of sexual function and general comfort of life due to recurrent infections of the vagina, vulva and urinary tract. Different therapeutic methods may benefit genitourinary syndrome of menopause (GSM), while innovative methods such as lasers or radiofrequency deserve further study in this area.
雌激素缺乏引起的围绝经期变化伴随着组织中胶原蛋白和弹性蛋白含量的减少，导致上皮变薄以及表层消失，进而导致平滑肌功能障碍和结缔组织退化。这一病因发病机制链导致约50%的围绝经期和绝经后女性出现一系列症状。由于阴道、外阴和尿道反复感染，干燥、烧灼感、性交困难和尿急等症状导致性功能质量和总体生活舒适度显著下降。不同的治疗方法可能对绝经后泌尿生殖综合征（GSM）有益，而激光或射频等创新方法在该领域值得进一步研究。
