Olamoyegun Michael A, Akinlade Akinyemi T, Ala Oluwabukola A
Department of Internal Medicine, Endocrinology, Diabetes & Metabolism Unit, Ladoke Akintola University of Technology, & LAUTECH Teaching Hospital, Ogbomoso, Oyo State, Nigeria.
Department of Medicine, General Hospital Odan, Lagos Nigeria.
Afr Health Sci. 2018 Dec;18(4):852-864. doi: 10.4314/ahs.v18i4.3.
Insulin is one of the most important anti-diabetic agents in the management of diabetes even among type 2 diabetic.
There was need to assess insulin adherence, mode of insulin delivery and burden of insulin usage among diabetics.
A cross-sectional, prospective questionnaire, orally administered at a Diabetes Clinic of a University Teaching Hospital, SouthWest, Nigeria. Participants were consecutive patients with diabetes who were 18 years or older presently on insulin either alone or in combination with other anti-diabetic agents for at least 3 months. Baseline demographic and insulin treatment information were obtained.
Two hundred and thirteen (213) participants were studied. Of these, 21 (9.9%) had T1DM and 192 (90.1%) had T2DM, (means age, 58.6 ± 13.1 years, mean duration of diabetes, 7.0 ± 6.9 years). Insulin adherence was noted in 72.8% with better adherence among those who self-injected insulin compared to those who were injected by health care professionals (HCPs) or relations. Among the respondents, 80.8% were on human insulin and pre-mixed insulin was the most commonly used form of insulin (52.6%). Most participants (52.6%) were taking 10-20 units per day, only 22 (10.3%) were on >40units/day. Reuse of insulin needle was found in 74.6% of the participants. Major reasons for insulin omission were non-availability of insulin and patients being tired of insulin injection.
The insulin adherence among diabetics in this study was high. Non-availability of insulin, insulin injection pain and being tired of continual insulin usage were some of the reasons for non-adherent to insulin usage.
胰岛素是糖尿病管理中最重要的抗糖尿病药物之一，即使在2型糖尿病患者中也是如此。
有必要评估糖尿病患者的胰岛素依从性、胰岛素给药方式及胰岛素使用负担。
在尼日利亚西南部一所大学教学医院的糖尿病诊所进行一项横断面、前瞻性问卷调查，通过口头方式进行。参与者为连续就诊的糖尿病患者，年龄在18岁及以上，目前单独使用胰岛素或与其他抗糖尿病药物联合使用胰岛素至少3个月。收集了基线人口统计学和胰岛素治疗信息。
共研究了213名参与者。其中，21例（9.9%）患有1型糖尿病，192例（90.1%）患有2型糖尿病（平均年龄58.6±13.1岁，平均糖尿病病程7.0±6.9年）。胰岛素依从性为72.8%，自我注射胰岛素者的依从性高于由医护人员或亲属注射胰岛素者。在受访者中，80.8%使用人胰岛素，预混胰岛素是最常用的胰岛素剂型（52.6%）。大多数参与者（52.6%）每天注射10 - 20单位，只有22例（10.3%）每天注射量>40单位。74.6%的参与者存在重复使用胰岛素针头的情况。胰岛素漏用的主要原因是胰岛素无法获取以及患者对胰岛素注射感到厌烦。
本研究中糖尿病患者的胰岛素依从性较高。胰岛素无法获取、胰岛素注射疼痛以及对持续使用胰岛素感到厌烦是不依从胰岛素治疗的部分原因。
