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加德纳综合征中的十二指肠绒毛状腺瘤和癌

Villous adenomas and carcinoma of the duodenum in Gardner's syndrome.

作者信息

Sinha J, Williamson R C

机构信息

Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

出版信息

Postgrad Med J. 1988 Nov;64(757):899-902. doi: 10.1136/pgmj.64.757.899.

DOI:10.1136/pgmj.64.757.899
PMID:3076670
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2429046/
Abstract

Patients with Gardner's syndrome are increasingly found to have polyps on routine upper gastrointestinal endoscopy, and their risk of developing periampullary carcinoma is between 3-12%. We report a 45 year old man with Gardner's syndrome who presented with periampullary carcinoma 5 years after colectomy. Review of the literature amassed another 21 cases of periampullary carcinoma in patients with Gardner's syndrome.

摘要

越来越多的Gardner综合征患者在常规上消化道内镜检查中被发现有息肉，他们发生壶腹周围癌的风险在3%至12%之间。我们报告一名45岁患有Gardner综合征的男性，他在结肠切除术后5年出现了壶腹周围癌。文献回顾又收集到另外21例Gardner综合征患者发生壶腹周围癌的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c1e/2429046/c8f35bed8dfd/postmedj00191-0063-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c1e/2429046/b57bf6aa5561/postmedj00191-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c1e/2429046/c8f35bed8dfd/postmedj00191-0063-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c1e/2429046/b57bf6aa5561/postmedj00191-0063-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c1e/2429046/c8f35bed8dfd/postmedj00191-0063-b.jpg

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1
Villous adenomas and carcinoma of the duodenum in Gardner's syndrome.加德纳综合征中的十二指肠绒毛状腺瘤和癌
Postgrad Med J. 1988 Nov;64(757):899-902. doi: 10.1136/pgmj.64.757.899.
2
Gardner's syndrome associated with carcinoma of the duodenal bulb: report of a case.加德纳综合征合并十二指肠球部癌：病例报告
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3
Upper gastrointestinal polyps in Gardner's syndrome.加德纳综合征中的上消化道息肉
Gastroenterology. 1984 Feb;86(2):295-301.
4
Gardner's syndrome associated with periampullary carcinoma, duodenal and gastric adenomatosis. Report of a case.加德纳综合征合并壶腹周围癌、十二指肠和胃腺瘤病。病例报告。
Dis Colon Rectum. 1982 Nov-Dec;25(8):766-71. doi: 10.1007/BF02553308.
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Extracolonic polyps in familial polyposis coli and Gardner's syndrome.家族性腺瘤性息肉病和加德纳综合征中的结肠外息肉
Dis Colon Rectum. 1985 Sep;28(9):664-8. doi: 10.1007/BF02553447.
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Gut. 1972 Jul;13(7):524-7. doi: 10.1136/gut.13.7.524.
7
[Multiple adenomas of the upper gastrointestinal tract with peripapillary carcinoma in Gardner syndrome].
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[Gardner's syndrome associated with periampullar carcinoma. Description of a case and review of the literature].[与壶腹周围癌相关的加德纳综合征。病例描述及文献复习]
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引用本文的文献

1
Carcinoma in adenoma of the ampulla of Vater synchronous with cancer of the sigmoid colon.壶腹腺瘤内癌与乙状结肠癌同时存在。
Dig Dis Sci. 1990 Feb;35(2):271-5. doi: 10.1007/BF01536776.

本文引用的文献

1
A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum.一项关于肠道息肉病的遗传学与临床研究，肠道息肉病是结肠癌和直肠癌的一个诱发因素。
Am J Hum Genet. 1951 Jun;3(2):167-76.
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Gardner's syndrome associated with periampullary carcinoma, duodenal and gastric adenomatosis. Report of a case.加德纳综合征合并壶腹周围癌、十二指肠和胃腺瘤病。病例报告。
Dis Colon Rectum. 1982 Nov-Dec;25(8):766-71. doi: 10.1007/BF02553308.
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Gardner syndrome and periampullary malignancy.
Am J Med Genet. 1980;6(3):205-19. doi: 10.1002/ajmg.1320060305.
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Adenocarcinoma and lymphoma of the small intestine. Distribution and etiologic associations.小肠腺癌和淋巴瘤。分布及病因学关联。
Ann Surg. 1983 Feb;197(2):172-8. doi: 10.1097/00000658-198302000-00008.
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Gardner's syndrome and periampullary malignancy.
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The Gardner syndrome: need for early diagnosis.
J Pediatr. 1968 Apr;72(4):497-505. doi: 10.1016/s0022-3476(68)80340-3.
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Familial polyposis coli associated with extracolonic abnormalities.家族性腺瘤性息肉病伴结肠外异常。
Gut. 1970 Apr;11(4):323-9. doi: 10.1136/gut.11.4.323.
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Gardner's syndrome; a revisit to a previously described family.加德纳综合征；对一个先前描述过的家族的再次研究。
Am J Dig Dis. 1970 Jun;15(6):551-68. doi: 10.1007/BF02238116.
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Gardner's syndrome: report of two families.加德纳综合征：两个家族的报告。
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[Gardner's syndrome associated with malignant degeneration of a polyp of Oddi's sphincter].
Acta Gastroenterol Belg. 1971 Aug-Sep;34(8):644-51.