Sugihara K, Muto T, Kamiya J, Konishi F, Sawada T, Morioka Y
Dis Colon Rectum. 1982 Nov-Dec;25(8):766-71. doi: 10.1007/BF02553308.
A 48-year-old man with Gardner's syndrome, who had abdominoperineal resection for rectal carcinoma in 1962, was found to have an ulcerating growth of the duodenum, and pancreaticoduodenectomy was performed in 1979. Histologic examination by complete step-serial sectioning disclosed a well-differentiated adenocarcinoma with adenomatous remnants, a large adenoma with focal carcinoma, 256 adenomas of the duodenum, and 91 adenomas of the gastric antrum. The world medical literature was reviewed, and 29 cases of periampullary carcinoma and 12 cases of gastric carcinoma complicating familial polyposis coli or Gardner's syndrome were analyzed.
一名48岁患有加德纳综合征的男性，于1962年因直肠癌接受了腹会阴联合切除术，1979年发现十二指肠有溃疡性肿物，遂行胰十二指肠切除术。通过完整的连续切片进行组织学检查发现，有一个伴有腺瘤残余的高分化腺癌、一个伴有局灶癌的大腺瘤、256个十二指肠腺瘤以及91个胃窦腺瘤。查阅了世界医学文献，并分析了29例壶腹周围癌以及12例并发家族性结肠息肉病或加德纳综合征的胃癌病例。
