Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine.
Clinical Epidemiology Unit, Istituto Dermopatico dell'Immacolata, IDI-IRCCS, Rome, Italy.
J Eur Acad Dermatol Venereol. 2019 Jul;33(7):1405-1411. doi: 10.1111/jdv.15496. Epub 2019 Mar 19.
The first dermatology-specific proxy health-related quality of life (HRQoL) instrument for children 0-4 years old with skin diseases, the Infants and Toddlers Dermatology Quality of Life (InToDermQoL), was recently developed. In order to avoid the problem of cross-cultural inequivalence focus groups work and pilot tests were organized simultaneously in all national centres of the project. The InToDermQoL showed good comprehensibility, clarity and acceptance.
To validate the InToDermQoL questionnaire during international field tests.
Internal consistency, test-retest reliability, convergent and discriminant validity of the InToDermQoL questionnaire were checked during international field tests.
Parents of 473 children with skin diseases filled in the national language versions of the InToDermQoL questionnaire. All three age-specific versions of the InToDermQoL questionnaire with 10, 12 and 15 items, respectively, showed high internal consistency (Cronbach's α 0.90-0.93), good test-retest reliability (correlation coefficients > 0.9), significant correlations with the most widely used atopic dermatitis-specific proxy instrument, the Infants Dermatitis Quality of Life Index (correlation coefficients 0.68-0.79). The InToDermQoL versions for children <3 years old well correlated with the atopic dermatis severity measure Scoring of Atopic Dermatitis (correlation coefficients 0.66 and 0.86 for 10 and 12 items versions, respectively). The InToDermQoL questionnaire discriminated well among different diagnoses and disease severity levels.
Our field tests confirmed internal consistency, test-retest reliability, convergent and discriminant validity of the InToDermQoL questionnaire. Development and validation of the InToDermQoL questionnaire make it possible to assess dermatology-specific aspects of HRQoL in youngest children with skin diseases. There are many reasons to assess HRQoL in dermatologic clinical practice, and we hope that our new instrument will be used internationally in paediatric dermatology for research and practical needs.
最近开发了一种专门针对 0-4 岁患有皮肤病的儿童的皮肤科特定代理健康相关生活质量 (HRQoL) 工具，即婴儿和学步儿童皮肤病生活质量 (InToDermQoL)。为了避免跨文化不等效问题，集中精力组织了焦点小组工作和试点测试在项目的所有国家中心同时进行。InToDermQoL 表现出良好的可理解性、清晰度和可接受性。
在国际现场测试中验证 InToDermQoL 问卷。
在国际现场测试中检查了 InToDermQoL 问卷的内部一致性、重测信度、收敛和判别效度。
473 名患有皮肤病的儿童的父母填写了本国语言版本的 InToDermQoL 问卷。分别具有 10、12 和 15 个项目的三个特定年龄的 InToDermQoL 问卷版本均显示出较高的内部一致性（Cronbach's α 0.90-0.93），良好的重测信度（相关系数>0.9），与最广泛使用的特应性皮炎特定代理工具，婴儿皮炎生活质量指数（相关系数 0.68-0.79）有显著相关性。对于<3 岁的儿童，InToDermQoL 版本与特应性皮炎严重程度测量评分特应性皮炎（10 项和 12 项版本的相关系数分别为 0.66 和 0.86）有很好的相关性。InToDermQoL 问卷在不同诊断和疾病严重程度水平之间有很好的区分度。
我们的现场测试证实了 InToDermQoL 问卷的内部一致性、重测信度、收敛性和判别效度。InToDermQoL 问卷的开发和验证使评估患有皮肤病的最年幼儿童的皮肤科特定 HRQoL 成为可能。在皮肤病学临床实践中评估 HRQoL 有很多原因，我们希望我们的新工具将在儿科皮肤病学中用于国际研究和实际需求。
