School of Sport and Exercise, University of Gloucestershire, Gloucester, UK.
Department of Exercise and Sport Science, University of North Carolina, Chapel Hill, NC, USA.
Exp Physiol. 2019 May;104(5):765-774. doi: 10.1113/EP087444. Epub 2019 Mar 25.
What is the central question of this study? There is growing interest in the effects of sedentarism on central and peripheral cardiovascular health. To permit further investigation, including larger epidemiological studies, there is a need to identify arterial health assessment tools that are valid (accurate) and reliable (precise), yet practical. What is the main finding and its importance? Lower-limb vascular health (femoral-ankle pulse-wave velocity) can be determined in a supine position with accuracy and precision using an oscillometrically based device. This technology might help to improve our understanding of the pathological mechanisms linking cardiovascular disease to sedentarism, including the interaction between peripheral and central vasculature.
There is a growing interest in the deleterious effects of sedentary behaviour on lower-limb arterial health. To permit further investigation, including larger epidemiological studies, there is a need to identify lower-limb arterial health assessment tools that are valid and reliable, yet simple to administer. In this study, we sought to determine the validity and between-day reliability of femoral-ankle pulse-wave velocity (faPWV) measures obtained using an oscillometrically based device (SphygmocCor XCEL) in supine and seated positions. Doppler ultrasound was used as the criterion. A total of 47 healthy adults were recruited for validity (n = 32) and reliability (n = 15) analyses. Validity was determined by measuring faPWV in seated and supine positions using the XCEL and Doppler ultrasound devices, in a randomized order. Between-day reliability was determined by measuring seated and supine faPWV using the XCEL on three different mornings, separated by a maximum of 7 days. The validity criterion [absolute standard error of estimate (aSEE) < 1.0 m s ] was met in the supine [aSEE = 0.8 m s , 95% confidence interval (CI) 0.4-1.0], but not in the seated (aSEE = 1.2 m s , 95% CI 1.1-1.2) position. Intraclass correlation coefficient (ICC) estimates revealed that the XCEL demonstrated good reliability in the supine position (ICC = 0.83, 95% CI 0.65-0.93), but poor reliability in the seated position (ICC = 0.29, 95% CI 0.23-0.63). The oscillometric XCEL device can be used to determine lower-limb pulse-wave velocity with acceptable validity and reliability in the conventionally recommended supine position, but not in the seated position.
本研究的核心问题是什么？久坐行为对中心和外周心血管健康的影响引起了越来越多的关注。为了进一步研究，包括更大规模的流行病学研究，有必要确定动脉健康评估工具具有准确性和可靠性，但又实用。主要发现及其重要性是什么？使用基于振荡的设备，仰卧位时下肢血管健康（股踝脉搏波速度）可准确且精确地确定。该技术可能有助于我们更好地理解将心血管疾病与久坐行为联系起来的病理机制，包括外周血管和中央血管之间的相互作用。
久坐行为对下肢动脉健康的有害影响引起了越来越多的关注。为了进一步研究，包括更大规模的流行病学研究，有必要确定动脉健康评估工具具有准确性和可靠性，但又简单易用。在这项研究中，我们旨在确定基于振荡的设备（SphygmocCor XCEL）在仰卧位和坐姿下测量股踝脉搏波速度（faPWV）的有效性和日内重复性。多普勒超声用作标准。共招募了 47 名健康成年人进行有效性（n=32）和可靠性（n=15）分析。有效性通过在随机顺序下使用 XCEL 和多普勒超声设备测量坐姿和仰卧位的 faPWV 来确定。日内重复性通过在三个不同的早晨使用 XCEL 测量坐姿和仰卧位的 faPWV 来确定，最大间隔为 7 天。有效性标准[绝对估计标准误差（aSEE）<1.0 m s]在仰卧位（aSEE=0.8 m s，95%置信区间（CI）0.4-1.0）中得到满足，但在坐姿中未得到满足（aSEE=1.2 m s，95% CI 1.1-1.2）位置。组内相关系数（ICC）估计值表明，XCEL 在仰卧位时具有良好的可靠性（ICC=0.83，95% CI 0.65-0.93），但在坐姿时可靠性较差（ICC=0.29，95% CI 0.23-0.63）。基于振荡的 XCEL 设备可用于在传统推荐的仰卧位确定下肢脉搏波速度，具有可接受的有效性和可靠性，但在坐姿中不可用。
