非关节性风湿病（“纤维炎综合征”）中的血浆色氨酸与肌肉骨骼疼痛
Plasma tryptophan and musculoskeletal pain in non-articular rheumatism ("fibrositis syndrome").
作者信息
Moldofsky Harvey, Warsh Jerry J
机构信息
Clinical Investigation Unit and Section of Neurochemistry, The Clarke Institute of Psychiatry, Toronto, Ont. M5T 1R8 Canada.
出版信息
Pain. 1978 Jun;5(1):65-71. doi: 10.1016/0304-3959(78)90025-8.
PMID:307724
Abstract
Plasma-free tryptophan is inversely related to the severity of subjective pain in 8 patients who fulfilled criteria for a variety of non-articular rheumatism, the "fibrositis syndrome". The observation is consistent with animal and human studies suggesting a relationship between reduced brain serotonin metabolism and pain reactivity.
摘要
在8名符合多种非关节性风湿病（“纤维肌痛综合征”）标准的患者中，游离血浆色氨酸与主观疼痛的严重程度呈负相关。该观察结果与动物和人体研究一致，这些研究表明脑血清素代谢降低与疼痛反应性之间存在关联。
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