Moldofsky Harvey, Warsh Jerry J
Clinical Investigation Unit and Section of Neurochemistry, The Clarke Institute of Psychiatry, Toronto, Ont. M5T 1R8 Canada.
Pain. 1978 Jun;5(1):65-71. doi: 10.1016/0304-3959(78)90025-8.
Plasma-free tryptophan is inversely related to the severity of subjective pain in 8 patients who fulfilled criteria for a variety of non-articular rheumatism, the "fibrositis syndrome". The observation is consistent with animal and human studies suggesting a relationship between reduced brain serotonin metabolism and pain reactivity.
在8名符合多种非关节性风湿病（“纤维肌痛综合征”）标准的患者中，游离血浆色氨酸与主观疼痛的严重程度呈负相关。该观察结果与动物和人体研究一致，这些研究表明脑血清素代谢降低与疼痛反应性之间存在关联。
