Boston Children's Hospital and Harvard Medical School, USA.
Harvard Graduate School of Education, USA.
Neural Plast. 2019 Jan 14;2019:1676285. doi: 10.1155/2019/1676285.
Experience plays an essential role in building brain architecture after birth. The question we address in this paper is what happens to brain and behavior when a young child is deprived of key experiences during critical periods of brain development. We focus in particular on the consequences of institutional rearing, with implication for the tens of millions of children around the world who from an early age experience profound psychosocial deprivation. Evidence is clear that deprivation can lead to a host of both short- and long-term consequences, including perturbations in brain structure and function, changes at cellular and molecular levels, and a plethora of psychological and behavioral impairments.
经验在出生后构建大脑结构方面起着至关重要的作用。我们在本文中探讨的问题是，当幼儿在大脑发育的关键时期被剥夺关键经验时，大脑和行为会发生什么变化。我们特别关注机构养育的后果，这对全世界数以千万计的幼儿产生了深远的心理社会剥夺影响。有证据表明，剥夺会导致一系列短期和长期的后果，包括大脑结构和功能的紊乱、细胞和分子水平的变化，以及大量的心理和行为障碍。
