Starace Michela, Alessandrini Aurora, Brandi Nicolò, Piraccini Bianca Maria
Department of Experimental, Diagnostic and Specialty Medicine-Division of_Dermatology, University of Bologna, Bologna, Italy.
Dermatol Pract Concept. 2019 Jan 31;9(1):38-43. doi: 10.5826/dpc.0901a10. eCollection 2019 Jan.
The term melanonychia describes a black-brown-gray pigmentation of the nail plate that, in most cases, appears as a longitudinal band. Melanonychia can be observed at any age, affecting one digit or several digits, in both fingernails and toenails. Its causes can be difficult to differentiate clinically and depend on the number of bands and on their color, edge, and width. For this reason, especially in adults and when the pigmentation is localized in one single digit, biopsy and histopathological examination still represent the gold standard for a definitive diagnosis. Dermoscopy should be used routinely in the evaluation of a pigmented nail, as it provides important information for the management of melanonychia and can help avoid unnecessary nail biopsies. In cases of melanonychia it is important to establish whether the pigment is melanin or not and to determine whether the pigmentation of melanin is due to activation or proliferation and whether it is benign or malignant.
甲黑线这一术语描述的是甲板上的黑褐色至灰色色素沉着,在大多数情况下表现为纵向条纹。甲黑线可在任何年龄出现,可累及一个或多个手指或脚趾的指甲。其病因在临床上可能难以鉴别,这取决于条纹的数量及其颜色、边缘和宽度。因此,尤其是在成年人中,当色素沉着局限于单个手指时,活检和组织病理学检查仍然是明确诊断的金标准。在评估色素沉着的指甲时应常规使用皮肤镜检查,因为它可为甲黑线的处理提供重要信息,并有助于避免不必要的指甲活检。对于甲黑线病例,确定色素是否为黑色素、确定黑色素沉着是由于激活还是增殖以及其是良性还是恶性非常重要。