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一只狗的肝叶发育不全。

Agenesis of hepatic lobes in a dog.

作者信息

Oishi Yasuhisa, Tani Kenji, Itamoto Kazuhito, Haraguchi Tomoya, Taura Yasuho

机构信息

Department of Veterinary Surgery, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1, Yoshida, Yamaguchi 753-8511, Japan.

Department of Animal Medical Center, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1, Yoshida, Yamaguchi 753-8511, Japan.

出版信息

Open Vet J. 2018;8(4):485-488. doi: 10.4314/ovj.v8i4.21. Epub 2018 Dec 27.

DOI:10.4314/ovj.v8i4.21
PMID:30775289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6356100/
Abstract

Agenesis of a hepatic lobe is an extremely rare congenital anomaly and only one dog have been reported in veterinary literature. We encountered a dog with this anomaly diagnosed by Computed tomography (CT) and portography. A two-year-old, 6.9-kg female Shih tzu dog was presented with vomiting and anorexia. The dog had no history of abdominal surgery or trauma. Biochemical analysis showed elevated plasmatic liver enzymes. CT revealed the absence of the liver parenchyma and vascular system of the left lobe, quadrate lobe and papillary process of the caudate lobe. A portosystemic shunt was also observed. The liver parenchyma and vascular system of these lobes were not detected under digital subtraction angiography during laparotomy. Furthermore, the liver parenchyma and vascular system of these lobes were not detected even when the remaining liver volume increased two months after treating the shunt vessel. CT proved itself a good option for antemortally diagnosis of hepatic agenesis in a dog.

摘要

肝叶发育不全是一种极其罕见的先天性异常,兽医文献中仅报道过一例犬病例。我们遇到一只通过计算机断层扫描(CT)和门静脉造影诊断出患有这种异常的犬。一只两岁、体重6.9千克的雌性西施犬出现呕吐和厌食症状。该犬无腹部手术或外伤史。生化分析显示血浆肝酶升高。CT显示左叶、方形叶和尾状叶乳头突的肝实质和血管系统缺失。还观察到一个门体分流。剖腹手术期间数字减影血管造影未检测到这些叶的肝实质和血管系统。此外,即使在治疗分流血管两个月后剩余肝脏体积增加,这些叶的肝实质和血管系统仍未检测到。CT证明是犬肝叶发育不全生前诊断的良好选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/62620b5dac0d/OpenVetJ-8-485-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/cc3a36b71072/OpenVetJ-8-485-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/5a408d26278d/OpenVetJ-8-485-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/616b409657c2/OpenVetJ-8-485-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/62620b5dac0d/OpenVetJ-8-485-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/cc3a36b71072/OpenVetJ-8-485-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/5a408d26278d/OpenVetJ-8-485-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/616b409657c2/OpenVetJ-8-485-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b95/6356100/62620b5dac0d/OpenVetJ-8-485-g004.jpg

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本文引用的文献

1
Multiple midline defects identified in a litter of golden retrievers following gestational administration of prednisone and doxycycline: a case series.一窝金毛猎犬在孕期使用泼尼松和强力霉素后出现多个中线缺陷:病例系列
BMC Vet Res. 2018 Mar 12;14(1):86. doi: 10.1186/s12917-018-1419-y.
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Agenesis of the left hepatic lobe undergoing laparoscopic hepatectomy for hepatocellular carcinoma: a case report.因肝细胞癌接受腹腔镜肝切除术的左肝叶发育不全:一例报告
Surg Case Rep. 2017 Dec;3(1):50. doi: 10.1186/s40792-017-0325-z. Epub 2017 Mar 29.
3
A rare congenital liver anomaly: Hypoplasia of left hepatic lobe.
一种罕见的先天性肝脏异常:左肝叶发育不全。
J Pak Med Assoc. 2016 Dec;66(12):1662-1664.
4
Ductal Plate Malformation in the Liver of Boxer Dogs: Clinical and Histological Features.拳师犬肝脏的导管板畸形:临床和组织学特征
Vet Pathol. 2016 May;53(3):602-13. doi: 10.1177/0300985815610567. Epub 2016 Jan 21.
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Anatomical evaluation of hepatic vascular system in healthy beagles using X-ray contrast computed tomography.使用X射线对比计算机断层扫描对健康比格犬肝脏血管系统进行解剖学评估。
J Vet Med Sci. 2015 Aug;77(8):925-9. doi: 10.1292/jvms.14-0469. Epub 2015 May 5.
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Agenesis of the right hepatic lobe.右肝叶发育不全
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Portal hypertension: pathophysiology, diagnosis, and treatment.门静脉高压症:病理生理学、诊断和治疗。
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Liver size, bodyweight, and tolerance to acute complete occlusion of congenital extrahepatic portosystemic shunts in dogs.犬先天性肝外门体分流急性完全闭塞时的肝脏大小、体重及耐受性
Vet Surg. 2008 Oct;37(7):656-62. doi: 10.1111/j.1532-950X.2008.00432.x.
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