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加热不燃烧烟草制品暴露会损害人气道细胞内稳态：与传统卷烟和电子烟的直接比较。

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

作者信息

Sohal Sukhwinder Singh, Eapen Mathew Suji, Naidu Vegi G M, Sharma Pawan

机构信息

Respiratory Translational Research Group, Dept of Laboratory Medicine, School of Health Sciences, University of Tasmania, Launceston, Australia.

Dept of Pharmacology, National Institute of Pharmaceutical Education & Research, Guwahati, India.

出版信息

ERJ Open Res. 2019 Feb 11;5(1). doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

DOI:10.1183/23120541.00159-2018

PMID:30775377

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6368999/

Abstract

http://ow.ly/wZ5P30ng8bU.

摘要

网址链接无法直接翻译为中文，其译文为：http://ow.ly/wZ5P30ng8bU. （可根据实际需求访问该链接获取相关内容）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a1/6368999/6fcd841aba27/00159-2018.01.jpg

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IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.加热不燃烧烟草制品暴露会损害人气道细胞内稳态：与传统卷烟和电子烟的直接比较。

ERJ Open Res. 2019 Feb 11;5(1). doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

2

Nicotine Delivery to the Aerosol of a Heat-Not-Burn Tobacco Product: Comparison With a Tobacco Cigarette and E-Cigarettes.加热不燃烧烟草制品气溶胶中尼古丁的传递：与传统卷烟和电子烟的比较。

Nicotine Tob Res. 2018 Jul 9;20(8):1004-1009. doi: 10.1093/ntr/ntx138.

3

Heat-not-burn tobacco product use in Japan: its prevalence, predictors and perceived symptoms from exposure to secondhand heat-not-burn tobacco aerosol.日本加热不燃烧烟草制品的使用情况：其流行率、预测因素以及接触二手加热不燃烧烟草气溶胶后的感知症状。

Tob Control. 2018 Jul;27(e1):e25-e33. doi: 10.1136/tobaccocontrol-2017-053947. Epub 2017 Dec 16.

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Vaping Smoking: A Quest for Efficacy and Safety of E-cigarette.电子烟与吸烟：对电子烟功效与安全性的探索

Curr Drug Saf. 2018;13(2):92-101. doi: 10.2174/1574886313666180227110556.

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Heat Not Burn Tobacco Product-A New Global Trend: Impact of Heat-Not-Burn Tobacco Products on Public Health, a Systematic Review.加热不燃烧烟草制品——一种新的全球趋势：加热不燃烧烟草制品对公共健康的影响：系统评价。

Int J Environ Res Public Health. 2020 Jan 8;17(2):409. doi: 10.3390/ijerph17020409.

6

Vascular endothelial function is impaired by aerosol from a single IQOS HeatStick to the same extent as by cigarette smoke.血管内皮功能因 IQOS HeatStick 的气溶胶而受损的程度与香烟烟雾相同。

Tob Control. 2018 Nov;27(Suppl 1):s13-s19. doi: 10.1136/tobaccocontrol-2018-054325. Epub 2018 Sep 11.

7

Harmful chemicals of heat not burn product and its induced oxidative stress of macrophages at air-liquid interface: Comparison with ultra-light cigarette.加热不燃烧产品的有害化学物质及其在气液界面诱导的巨噬细胞氧化应激：与极轻卷烟的比较。

Toxicol Lett. 2020 Oct 1;331:200-207. doi: 10.1016/j.toxlet.2020.06.017. Epub 2020 Jun 20.

8

Passive exposure to pollutants from conventional cigarettes and new electronic smoking devices (IQOS, e-cigarette) in passenger cars.在汽车内被动接触传统香烟和新型电子吸烟装置（IQOS，电子烟）中的污染物。

Int J Hyg Environ Health. 2019 Apr;222(3):486-493. doi: 10.1016/j.ijheh.2019.01.003. Epub 2019 Jan 23.

9

Smoking E-CigaRette and HEat-noT-burn products: validation of the SECRHET questionnaire.吸食电子烟和加热不燃烧产品：SECRHET问卷的验证

Clin Ter. 2019 Jul-Aug;170(4):e247-e251. doi: 10.7417/CT.2019.2142.

10

A Comparison of Flavorless Electronic Cigarette-Generated Aerosol and Conventional Cigarette Smoke on the Planktonic Growth of Common Oral Commensal Streptococci.无味电子烟气溶胶与传统卷烟烟雾对常见口腔共生链球菌浮游生长的比较。

Int J Environ Res Public Health. 2019 Dec 9;16(24):5004. doi: 10.3390/ijerph16245004.

引用本文的文献

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Large Emphysematous Bulla After IQOS Use: A Case-Based Literature Review.使用 IQOS 后出现的巨大气肿性肺大疱：基于病例的文献综述

Diagnostics (Basel). 2025 Sep 8;15(17):2267. doi: 10.3390/diagnostics15172267.

2

Almost 20 years have passed: a view of heated tobacco and vape.近20年过去了：对加热烟草和电子烟的一种看法。

Eur Heart J Suppl. 2025 Apr 16;27(Suppl 3):iii25-iii27. doi: 10.1093/eurheartjsupp/suaf037. eCollection 2025 Mar.

3

Nicotine is an Immunosuppressant: Implications for Women's Health and Disease.尼古丁是一种免疫抑制剂：对女性健康与疾病的影响。

本文引用的文献

1

Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette.新型加热烟草制品（IQOS）的羰基排放物：与电子烟和普通卷烟的比较。

Addiction. 2018 Nov;113(11):2099-2106. doi: 10.1111/add.14365. Epub 2018 Jul 10.

2

E-cigarette vapour enhances pneumococcal adherence to airway epithelial cells.电子烟蒸汽增强肺炎链球菌对气道上皮细胞的黏附。

Eur Respir J. 2018 Feb 7;51(2). doi: 10.1183/13993003.01592-2017. Print 2018 Feb.

3

Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.

加热不燃烧烟草制品暴露会损害人气道细胞内稳态：与传统卷烟和电子烟的直接比较。

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

作者信息

Sohal Sukhwinder Singh, Eapen Mathew Suji, Naidu Vegi G M, Sharma Pawan

机构信息

Respiratory Translational Research Group, Dept of Laboratory Medicine, School of Health Sciences, University of Tasmania, Launceston, Australia.

Dept of Pharmacology, National Institute of Pharmaceutical Education & Research, Guwahati, India.

出版信息

ERJ Open Res. 2019 Feb 11;5(1). doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

DOI:10.1183/23120541.00159-2018

PMID:30775377

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6368999/

Abstract

http://ow.ly/wZ5P30ng8bU.

摘要

网址链接无法直接翻译为中文，其译文为：http://ow.ly/wZ5P30ng8bU. （可根据实际需求访问该链接获取相关内容）

相似文献

1

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.加热不燃烧烟草制品暴露会损害人气道细胞内稳态：与传统卷烟和电子烟的直接比较。

ERJ Open Res. 2019 Feb 11;5(1). doi: 10.1183/23120541.00159-2018. eCollection 2019 Feb.

2

Nicotine Delivery to the Aerosol of a Heat-Not-Burn Tobacco Product: Comparison With a Tobacco Cigarette and E-Cigarettes.加热不燃烧烟草制品气溶胶中尼古丁的传递：与传统卷烟和电子烟的比较。

Nicotine Tob Res. 2018 Jul 9;20(8):1004-1009. doi: 10.1093/ntr/ntx138.

3

Heat-not-burn tobacco product use in Japan: its prevalence, predictors and perceived symptoms from exposure to secondhand heat-not-burn tobacco aerosol.日本加热不燃烧烟草制品的使用情况：其流行率、预测因素以及接触二手加热不燃烧烟草气溶胶后的感知症状。

Tob Control. 2018 Jul;27(e1):e25-e33. doi: 10.1136/tobaccocontrol-2017-053947. Epub 2017 Dec 16.

4

Vaping Smoking: A Quest for Efficacy and Safety of E-cigarette.电子烟与吸烟：对电子烟功效与安全性的探索

Curr Drug Saf. 2018;13(2):92-101. doi: 10.2174/1574886313666180227110556.

5

Heat Not Burn Tobacco Product-A New Global Trend: Impact of Heat-Not-Burn Tobacco Products on Public Health, a Systematic Review.加热不燃烧烟草制品——一种新的全球趋势：加热不燃烧烟草制品对公共健康的影响：系统评价。

Int J Environ Res Public Health. 2020 Jan 8;17(2):409. doi: 10.3390/ijerph17020409.

6

Vascular endothelial function is impaired by aerosol from a single IQOS HeatStick to the same extent as by cigarette smoke.血管内皮功能因 IQOS HeatStick 的气溶胶而受损的程度与香烟烟雾相同。

Tob Control. 2018 Nov;27(Suppl 1):s13-s19. doi: 10.1136/tobaccocontrol-2018-054325. Epub 2018 Sep 11.

7

Harmful chemicals of heat not burn product and its induced oxidative stress of macrophages at air-liquid interface: Comparison with ultra-light cigarette.加热不燃烧产品的有害化学物质及其在气液界面诱导的巨噬细胞氧化应激：与极轻卷烟的比较。

Toxicol Lett. 2020 Oct 1;331:200-207. doi: 10.1016/j.toxlet.2020.06.017. Epub 2020 Jun 20.

8

Passive exposure to pollutants from conventional cigarettes and new electronic smoking devices (IQOS, e-cigarette) in passenger cars.在汽车内被动接触传统香烟和新型电子吸烟装置（IQOS，电子烟）中的污染物。

Int J Hyg Environ Health. 2019 Apr;222(3):486-493. doi: 10.1016/j.ijheh.2019.01.003. Epub 2019 Jan 23.

9

Smoking E-CigaRette and HEat-noT-burn products: validation of the SECRHET questionnaire.吸食电子烟和加热不燃烧产品：SECRHET问卷的验证

Clin Ter. 2019 Jul-Aug;170(4):e247-e251. doi: 10.7417/CT.2019.2142.

10

A Comparison of Flavorless Electronic Cigarette-Generated Aerosol and Conventional Cigarette Smoke on the Planktonic Growth of Common Oral Commensal Streptococci.无味电子烟气溶胶与传统卷烟烟雾对常见口腔共生链球菌浮游生长的比较。

Int J Environ Res Public Health. 2019 Dec 9;16(24):5004. doi: 10.3390/ijerph16245004.

引用本文的文献

1

Large Emphysematous Bulla After IQOS Use: A Case-Based Literature Review.使用 IQOS 后出现的巨大气肿性肺大疱：基于病例的文献综述

Diagnostics (Basel). 2025 Sep 8;15(17):2267. doi: 10.3390/diagnostics15172267.

2

Almost 20 years have passed: a view of heated tobacco and vape.近20年过去了：对加热烟草和电子烟的一种看法。

Eur Heart J Suppl. 2025 Apr 16;27(Suppl 3):iii25-iii27. doi: 10.1093/eurheartjsupp/suaf037. eCollection 2025 Mar.

3

Nicotine is an Immunosuppressant: Implications for Women's Health and Disease.尼古丁是一种免疫抑制剂：对女性健康与疾病的影响。

本文引用的文献

1

Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette.新型加热烟草制品（IQOS）的羰基排放物：与电子烟和普通卷烟的比较。

Addiction. 2018 Nov;113(11):2099-2106. doi: 10.1111/add.14365. Epub 2018 Jul 10.

2

E-cigarette vapour enhances pneumococcal adherence to airway epithelial cells.电子烟蒸汽增强肺炎链球菌对气道上皮细胞的黏附。

Eur Respir J. 2018 Feb 7;51(2). doi: 10.1183/13993003.01592-2017. Print 2018 Feb.

3

Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.

J Neuroimmunol. 2024 Dec 15;397:578468. doi: 10.1016/j.jneuroim.2024.578468. Epub 2024 Oct 20.

4

Comparison of smoking conventional cigarettes and using heated tobacco products on the olfactory and gustatory function in healthy young adults: A cross-sectional study.健康年轻成年人中吸食传统香烟与使用加热烟草制品对嗅觉和味觉功能影响的比较：一项横断面研究

Tob Induc Dis. 2024 Sep 11;22. doi: 10.18332/tid/192524. eCollection 2024.

5

Tobacco and COPD: presenting the World Health Organization (WHO) Tobacco Knowledge Summary.烟草与 COPD：介绍世界卫生组织（WHO）烟草知识摘要。

Respir Res. 2024 Sep 11;25(1):338. doi: 10.1186/s12931-024-02961-5.

6

A scoping review of the toxicity and health impact of IQOS.对IQOS毒性及健康影响的范围综述。

Tob Induc Dis. 2024 Jun 3;22. doi: 10.18332/tid/188867. eCollection 2024.

7

Association between heated tobacco product use and airway obstruction: a single-centre observational study, Japan.加热烟草制品使用与气道阻塞的相关性：一项单中心观察性研究，日本。

BMJ Open Respir Res. 2024 Mar 9;11(1):e001793. doi: 10.1136/bmjresp-2023-001793.

8

Heated tobacco product IQOS induces unique metabolic signatures in human bronchial epithelial cells.加热烟草制品IQOS在人支气管上皮细胞中诱导独特的代谢特征。

ERJ Open Res. 2024 Mar 4;10(2). doi: 10.1183/23120541.00805-2023. eCollection 2024 Mar.

9

Nicotine and Cardiovascular Health: When Poison is Addictive - a WHF Policy Brief.尼古丁与心血管健康：当毒药成瘾时——世界心脏联盟政策简报

Glob Heart. 2024 Jan 31;19(1):14. doi: 10.5334/gh.1292. eCollection 2024.

10

Immunology in COPD and the use of combustible cigarettes and heated tobacco products.慢性阻塞性肺疾病中的免疫学及可燃香烟和加热烟草产品的使用。

Eur J Med Res. 2023 Oct 4;28(1):397. doi: 10.1186/s40001-023-01374-2.

长期吸入含尼古丁的电子烟烟雾会破坏小鼠气道屏障功能，引发全身炎症和多器官纤维化。

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R834-R847. doi: 10.1152/ajpregu.00270.2017. Epub 2018 Jan 31.

4

Heat-not-burn tobacco products: concerns from the Italian experience.加热不燃烧烟草制品：来自意大利经验的担忧。

Tob Control. 2019 Jan;28(1):113-114. doi: 10.1136/tobaccocontrol-2017-054054. Epub 2018 Jan 26.

5

Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer.线粒体功能障碍：癌症中上皮-间充质转化的一种新型潜在驱动因素

Front Oncol. 2017 Dec 1;7:295. doi: 10.3389/fonc.2017.00295. eCollection 2017.

6

Heat-not-burn tobacco product use in Japan: its prevalence, predictors and perceived symptoms from exposure to secondhand heat-not-burn tobacco aerosol.日本加热不燃烧烟草制品的使用情况：其流行率、预测因素以及接触二手加热不燃烧烟草气溶胶后的感知症状。

Tob Control. 2018 Jul;27(e1):e25-e33. doi: 10.1136/tobaccocontrol-2017-053947. Epub 2017 Dec 16.

7

Trajectories of E-Cigarette and Conventional Cigarette Use Among Youth.青少年电子烟和传统香烟使用轨迹。

Pediatrics. 2018 Jan;141(1). doi: 10.1542/peds.2017-1832. Epub 2017 Dec 4.

8

Maternal E-Cigarette Exposure in Mice Alters DNA Methylation and Lung Cytokine Expression in Offspring.母鼠电子烟暴露可改变子代 DNA 甲基化和肺细胞因子表达。

Am J Respir Cell Mol Biol. 2018 Mar;58(3):366-377. doi: 10.1165/rcmb.2017-0206RC.

9

Short-term respiratory effects of e-cigarettes in healthy individuals and smokers with asthma.电子烟对健康个体和哮喘吸烟者短期呼吸影响的研究。

Respirology. 2018 Mar;23(3):291-297. doi: 10.1111/resp.13180. Epub 2017 Sep 24.

10

Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease.上皮-间质转化：一系列状态及其在肺发育、稳态维持和疾病中的作用

Dev Dyn. 2018 Mar;247(3):346-358. doi: 10.1002/dvdy.24541. Epub 2017 Jul 21.

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加热不燃烧烟草制品暴露会损害人气道细胞内稳态：与传统卷烟和电子烟的直接比较。

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

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机构信息

出版信息

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引用本文的文献

本文引用的文献

加热不燃烧烟草制品暴露会损害人气道细胞内稳态：与传统卷烟和电子烟的直接比较。

IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette.

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出版信息

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引用本文的文献

本文引用的文献