Takahashi Mizuna, Uchida Keiichi, Yamada Shinichiro, Sugino Noriyuki, Higashi Yukihito, Yamada Kazuhiro, Taguchi Akira
Department of Hard Tissue Research, Graduate School of Oral Medicine, Matsumoto Dental University, 1170 Gobara, Hirooka, Shiojiri 399-0781, Japan.
Department of Orthodontics, School of Dentistry, Matsumoto Dental University, 1170 Gobara, Hirooka, Shiojiri 399-0781, Japan.
Osteoporos Sarcopenia. 2016 Dec;2(4):250-255. doi: 10.1016/j.afos.2016.10.001. Epub 2016 Oct 25.
Mandibular cortical erosion detected on dental panoramic radiographs is associated with increased risk of osteoporosis in older adults. Additionally, many reports have demonstrated an association between decreased number of teeth present and osteoporosis. However, whether mandibular cortical erosion is associated with a decreased number of teeth remains unclear. The purpose of this study, therefore, was to clarify the association between mandibular cortical erosion and number of teeth present in Japanese men and women aged 40 years and older. Among patients who visited our university hospital and underwent dental panoramic radiography for the diagnosis of dental diseases, 839 patients (293 men and 546 women) aged 40-89 years (mean [SD], 63.7 [10.6] years) participated in this study. Multiple regression analysis revealed that mildly to moderately eroded cortex (p = 0.007) and severe eroded cortex (p < 0.001) were significantly associated with a decreased number of teeth present. Analysis of covariance adjusted for covariates revealed a significant association between mandibular cortical erosion category and number of teeth present (p < 0.001). Subjects with a severely eroded cortex had significantly fewer teeth present than those with a normal cortex (mean [SE], 20.7 [0.5] vs. 23.4 [0.3], p < 0.001) or mildly to moderately eroded cortex (22.2 [0.4], p = 0.04). Subjects with a mildly to moderately eroded cortex had significantly fewer teeth present than those with a normal cortex (p = 0.033). Our results suggest the significant association between mandibular cortical erosion and number of teeth present in Japanese men and women aged 40 years and older.
在牙科全景X线片上检测到的下颌骨皮质侵蚀与老年人骨质疏松风险增加相关。此外，许多报告表明现存牙齿数量减少与骨质疏松之间存在关联。然而，下颌骨皮质侵蚀是否与牙齿数量减少相关仍不清楚。因此，本研究的目的是阐明40岁及以上日本男性和女性下颌骨皮质侵蚀与现存牙齿数量之间的关联。在到我们大学医院就诊并接受牙科全景X线摄影以诊断牙科疾病的患者中，839名年龄在40 - 89岁（平均[标准差]，63.7[10.6]岁）的患者（293名男性和546名女性）参与了本研究。多元回归分析显示，轻度至中度侵蚀的皮质（p = 0.007）和重度侵蚀的皮质（p < 0.001）与现存牙齿数量减少显著相关。对协变量进行调整后的协方差分析显示，下颌骨皮质侵蚀类别与现存牙齿数量之间存在显著关联（p < 0.001）。皮质严重侵蚀的受试者现存牙齿明显少于皮质正常的受试者（平均[标准误]，20.7[0.5]对23.4[0.3]，p < 0.001）或轻度至中度侵蚀的皮质（22.2[0.4]，p = 0.04）。轻度至中度侵蚀皮质的受试者现存牙齿明显少于皮质正常的受试者（p = 0.033）。我们的结果表明，40岁及以上日本男性和女性的下颌骨皮质侵蚀与现存牙齿数量之间存在显著关联。
