Jang Ki-Mo, Cho Kyung-Hwan, Lee Soon-Hyuck, Han Seung-Beom, Han Kyung-Do, Kim Yang-Hyun
Department of Orthopaedic Surgery, Anam Hospital, Korea University College of Medicine, Seoul, South Korea.
Department of Family Medicine, Anam Hospital, Korea University College of Medicine, Seoul, South Korea.
Maturitas. 2015 Dec;82(4):360-4. doi: 10.1016/j.maturitas.2015.07.016. Epub 2015 Jul 26.
The current study aimed to investigate the association between the number of remaining teeth and bone mineral density (BMD) using data from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2010.
This study enrolled 7315 Korean subjects (3364 men over 50 years of age and 3951 postmenopausal women). BMD was measured using dual-energy X-ray absorptiometry at three sites: the total femur (TF), femur neck (FN), and lumbar spine (LS). The number of teeth present was categorized into four groups (≤10, 11-20, 21-25, and ≥26 teeth).
More remaining teeth were significantly associated with a higher BMD at the TF, FN, and LS in postmenopausal women after adjusting for all the covariates, but not in elderly men. In both sexes, subjects with a normal BMD tended to have more remaining teeth than those who were diagnosed with osteopenia and osteoporosis. A lower prevalence of osteoporosis was also significantly associated with more remaining teeth (number of teeth ≥26) in postmenopausal women. This trend was statistically significant in osteoporosis at the FN (p for trend=0.019).
The number of remaining teeth was associated with osteoporosis, especially at the FN, in postmenopausal women.
本研究旨在利用2008 - 2010年韩国国民健康与营养检查调查(KNHANES)的数据,调查剩余牙齿数量与骨矿物质密度(BMD)之间的关联。
本研究纳入了7315名韩国受试者(3364名50岁以上男性和3951名绝经后女性)。使用双能X线吸收法在三个部位测量骨密度:全股骨(TF)、股骨颈(FN)和腰椎(LS)。现存牙齿数量分为四组(≤10颗、11 - 20颗、21 - 25颗和≥26颗牙齿)。
在调整所有协变量后,绝经后女性中,更多的剩余牙齿与TF、FN和LS处更高的骨密度显著相关,但在老年男性中并非如此。在男女两性中,骨密度正常的受试者往往比被诊断为骨质减少和骨质疏松的受试者有更多的剩余牙齿。绝经后女性中,较低的骨质疏松患病率也与更多的剩余牙齿(牙齿数量≥26颗)显著相关。这种趋势在FN处的骨质疏松中具有统计学意义(趋势p值 = 0.019)。
绝经后女性的剩余牙齿数量与骨质疏松有关,尤其是在FN处。