Instituto de Ciencias e Innovación en Medicina, and Millennium Nucleus for Collaborative Reseach on Bacterial Resistance (MICROB-R), Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago,Chile.
Division of Infectious Diseases, Rhode Island Hospital, Brown University, Providence, Rhode Island,United States.
Infect Control Hosp Epidemiol. 2019 May;40(5):585-589. doi: 10.1017/ice.2019.28. Epub 2019 Feb 19.
The human microbiome participates in numerous aspects of human physiology and disease states. Recently, studies have begun to explore the role of the microbiome in colonization, infection and transmission of pathogens. This review provides a summary of the methodological principles used in microbiome studies and the published evidence of the impact of microbiome dysbiosis in infection prevention.
人类微生物组参与了人类生理学和疾病状态的许多方面。最近,研究已经开始探索微生物组在病原体定植、感染和传播中的作用。本综述提供了微生物组研究中使用的方法学原理的总结,并发表了微生物组失调对感染预防影响的证据。