Tominaga Kentaro, Tsuchiya Atsunori, Sato Hiroki, Kimura Atsushi, Oda Chiyumi, Hosaka Kazunori, Kawata Yuzo, Kimura Naruhiro, Hayashi Kazunao, Yokoyama Junji, Terai Shuji
Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, 1-757, Aasahimachi-Dori, Chuo-Ku, Niigata, Niigata, 9518510, Japan.
Clin J Gastroenterol. 2019 Jun;12(3):243-246. doi: 10.1007/s12328-019-00939-1. Epub 2019 Feb 18.
Ulcerative colitis (UC) is a chronic and recurrent inflammatory disease involving the intestine, and Guillain-Barré Syndrome (GBS) is rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. UC and GBS can be caused by immune system abnormalities and can co-exist. To date, there are 7 reported cases of GBS in patients with UC. However, only one patient developed UC after GBS treatment. We report a rare case of UC that appeared after intravenous immunoglobulin therapy for GBS. This case report and literature review will allow accurate and prompt diagnosis of co-existent GBS and UC.
溃疡性结肠炎（UC）是一种累及肠道的慢性复发性炎症性疾病，而吉兰 - 巴雷综合征（GBS）是由免疫系统损害周围神经系统引起的急性起病的肌肉无力。UC和GBS可由免疫系统异常引起，且可能共存。迄今为止，已有7例UC患者并发GBS的报道。然而，仅有1例患者在GBS治疗后发生UC。我们报告1例罕见的GBS患者在静脉注射免疫球蛋白治疗后出现UC的病例。本病例报告及文献复习将有助于准确、及时地诊断GBS与UC并存的情况。
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