Miyares C, Hollands I, Castañeda C, González T, Fragoso T, Currás R, Soria C
Centro de Histoterapia Placentaria, La Habana, Cuba.
Acta Gastroenterol Latinoam. 1988;18(3):195-201.
The results of a clinic assay with an extract made out of propolis (bee glue) or "Propolisina" were showed with the aim of showing its effectivity against giardiasis. One hundred and thirty eight patients were studied 48 children and 90 adults, in 2 groups and they selected aleatorily to be treated with "Propolosina" or an imidazole derivate (tinidazole). The method for an exact diagnosis in children was duodenal aspiration and in adults duodenal mucosa frotis by means of duodenoscopy. Similar studies were carried out as a cure criterium in a 5-day term after being through with the treatment. Propolisina was used with different concentrations: in children (concentration at 10%) results showed a 52% cure. In 40 adults (concentration at 20%) it was obtained a similar result to that of tinidazole; and when propolisina concentration was elevated at 30% in the remaining 50 patients there was a higher effectivity (60 of cure Vs 40% with tinidazole). This work shows the success of this natural product, which is very easy to obtain in Cuba and with no side effects in the treatment of this intestinal parasitism, what is of great economical importance for our countries.
展示了用蜂胶提取物或“Propolisina”进行临床检测的结果，目的是表明其对贾第虫病的有效性。对138名患者进行了研究，其中48名儿童和90名成人，分为两组，随机选择用“Propolosina”或咪唑衍生物（替硝唑）进行治疗。儿童的确切诊断方法是十二指肠抽吸，成人则通过十二指肠镜检查获取十二指肠黏膜刮片。治疗结束后，在5天内进行了类似研究作为治愈标准。Propolisina使用了不同浓度：在儿童中（浓度为10%），结果显示治愈率为52%。在40名成人中（浓度为20%），得到了与替硝唑相似的结果；当在其余50名患者中将Propolisina浓度提高到30%时，有更高的有效性（治愈率60%，而替硝唑为40%）。这项工作表明了这种天然产物的成功，它在古巴很容易获得，并且在治疗这种肠道寄生虫病时没有副作用，这对我们国家具有重要的经济意义。
