Hamouda Waeel Ossama
Department of Neurosurgery, Cairo University Medical School and Teaching Hospitals, Cairo, Egypt.
J Craniovertebr Junction Spine. 2018 Oct-Dec;9(4):227-231. doi: 10.4103/jcvjs.JCVJS_83_18.
Dysphagia in old patients secondary to diffuse idiopathic skeletal hyperostosis (DISH) syndrome is underdiagnosed. Surgical resection of the offending osteophytes is the definitive treatment. However, the timing of surgery in the course of the disease is still controversial. The study tries to find a correlation if any, between the timing of osteophytectomy surgery aimed to relieve DISH syndrome-induced dysphagia and the surgical outcome.
During the period from 2010 to 2015, clinical and radiological data of patients who presented with dysphagia attributed to DISH syndrome were retrospectively reviewed along with their management and outcome.
One female and seven male patients were included in the study. Mean age was 71 years. Mean duration of dysphagia was 3 years and 10 months. Surgical resection was attempted through anterolateral cervical approach in five cases who were fit for surgery, in which four showed complete resolution of dysphagia (one experienced transient hoarseness of voice for 4 weeks postoperatively), and the fifth showed minimal improvement after limited resection due to intraoperative finding of marked esophageal adherence to osteophytes. The two unfavorable outcomes (subtotal resection and transient hoarseness of voice) occurred in relatively older patients (average: 75.5 years) with longer standing dysphagia (average: 7 years).
DISH syndrome as a cause of dysphagia is commonly underlooked. Surgical resection of the offending osteophytes through an anterolateral approach is a safe and effective procedure. For patients who are fit for surgery, older age or longer duration of dysphagia might be associated with less favorable surgical outcome.
弥漫性特发性骨肥厚(DISH)综合征继发的老年患者吞咽困难诊断不足。切除引起问题的骨赘是确定性治疗方法。然而,疾病过程中手术时机仍存在争议。本研究试图找出旨在缓解DISH综合征所致吞咽困难的骨赘切除术时机与手术结果之间是否存在关联。
回顾性分析2010年至2015年期间因DISH综合征出现吞咽困难患者的临床和影像学资料,以及他们的治疗情况和结果。
研究纳入1名女性和7名男性患者。平均年龄71岁。吞咽困难平均持续时间为3年10个月。5例适合手术的患者通过颈前外侧入路尝试手术切除,其中4例吞咽困难完全缓解(1例术后出现4周短暂声音嘶哑),第5例因术中发现食管与骨赘明显粘连,有限切除后改善轻微。这两个不良结果(次全切除和短暂声音嘶哑)发生在年龄相对较大(平均75.5岁)、吞咽困难病程较长(平均7年)的患者中。
DISH综合征作为吞咽困难的病因常被忽视。通过颈前外侧入路切除引起问题的骨赘是一种安全有效的手术方法。对于适合手术的患者,年龄较大或吞咽困难病程较长可能与较差的手术结果相关。