Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.
Immunity. 2019 Feb 19;50(2):285-287. doi: 10.1016/j.immuni.2019.01.018.
IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Their findings provide insight into the differentiation of IgE cells in humans and have implications for our understanding of allergic disease.
IgE 抗体是过敏反应的重要介质。在最近发表于《科学》杂志的一项研究中,Croote 等人(2018 年)对花生过敏个体中分离出的 IgE 细胞进行了描述。他们的发现为理解人类 IgE 细胞的分化提供了线索,并对我们理解过敏疾病具有重要意义。