Al Yousef Sulaiman A, Taha Eihab M
Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Dammam, Hafr Al Batin, Saudi Arabia.
Saudi J Med Med Sci. 2016 Jan-Apr;4(1):2-8. doi: 10.4103/1658-631X.170880. Epub 2015 Dec 2.
Methicillin-resistant (MRSA) infections in hospital have obviously imposed a significant burden of morbidity and mortality, and strain on healthcare resources. Here, we review the genotype distribution of these pathogens in the Kingdom of Saudi Arabia (KSA). A PubMed literature search (until May 2014) specified 12 articles that characterized MRSA clones in KSA. Only two regions (Riyadh and Damamm) were represented in ten articles. Data from these articles showed that the pandemic Vienna/Hungarian/Brazilian clone (CC8/ST239-III) is the most frequent in Saudi regions (Riyadh and Damamm). Several other clones such as Barnim/UK-EMRSA-15 (CC22-IV), Southwest Pacific clone (ST30-IV) and European community-associated-MRSA clone (CC80-IV) have been detected in the Riyadh region. A variety of MRSA clones is beginning to circulate in Saudi hospitals. Continued collection and molecular characterization of MRSA is crucial for the effective prevention and treatment.
医院中的耐甲氧西林金黄色葡萄球菌(MRSA)感染显然已造成了巨大的发病和死亡负担,并给医疗资源带来了压力。在此,我们综述了沙特阿拉伯王国(KSA)这些病原体的基因型分布情况。一项PubMed文献检索(截至2014年5月)确定了12篇描述KSA中MRSA克隆的文章。只有两个地区(利雅得和达曼)在10篇文章中有相关描述。这些文章的数据表明,流行的维也纳/匈牙利/巴西克隆株(CC8/ST239-III)在沙特地区(利雅得和达曼)最为常见。在利雅得地区还检测到了其他几种克隆株,如巴尔尼姆/英国-耐甲氧西林金黄色葡萄球菌-15(CC22-IV)、西南太平洋克隆株(ST30-IV)和欧洲社区相关-耐甲氧西林金黄色葡萄球菌克隆株(CC80-IV)。多种MRSA克隆株开始在沙特医院中传播。持续收集MRSA并进行分子特征分析对于有效预防和治疗至关重要。