白色念珠菌的分子遗传学
The molecular genetics of Candida albicans.
作者信息
Kurtz M B, Kirsch D R, Kelly R
机构信息
Squibb Institute for Medical Research, Department of Microbial Biochemistry and Genetics, Princeton, New Jersey 08540.
出版信息
Microbiol Sci. 1988 Feb;5(2):58-63.
PMID:3079219
Abstract
Candida albicans, the major fungal pathogen of humans, is a diploid with no known sexual cycle. Recent genetic studies in C. albicans include the physical characterization of the genome, the development of systems for parasexual genetics, the cloning of Candida genes, and the development of methods for integrative and ARS-mediated transformation as well as gene disruption.
摘要
白色念珠菌是人类主要的真菌病原体，是一种没有已知有性生殖周期的二倍体。最近关于白色念珠菌的遗传学研究包括基因组的物理特征分析、准性遗传学系统的开发、念珠菌基因的克隆，以及整合和ARS介导的转化及基因破坏方法的开发。
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