Sullivan Sheena G, Price Olivia H, Regan Annette K
WHO Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, 792 Elizabeth St, Melbourne, Victoria 3000, Australia.
WHO Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Ther Adv Vaccines Immunother. 2019 Feb 7;7:2515135519826481. doi: 10.1177/2515135519826481. eCollection 2019.
Vaccination is the most practical means available for preventing influenza. Influenza vaccines require frequent updates to keep pace with antigenic drift of the virus, and the effectiveness, and sometimes the safety, of the vaccine can therefore vary from season to season. Three key populations that the World Health Organization recommends should be prioritized for influenza vaccination are pregnant women, children younger than 5 years of age and the elderly. This review discusses the burden of influenza and the safety and effectiveness profile of influenza vaccines recommended for these groups.
接种疫苗是预防流感最切实可行的方法。流感疫苗需要频繁更新以跟上病毒的抗原漂移，因此疫苗的有效性，有时还有安全性，可能会因季节而异。世界卫生组织建议应优先接种流感疫苗的三个关键人群是孕妇、5岁以下儿童和老年人。本综述讨论了流感的负担以及针对这些人群推荐的流感疫苗的安全性和有效性概况。
