• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Successful treatment of refractory mechanic's hands with ustekinumab in a patient with the antisynthetase syndrome.用优特克单抗成功治疗一名患有抗合成酶综合征患者的难治性机械工手。
Rheumatology (Oxford). 2019 Jul 1;58(7):1307-1308. doi: 10.1093/rheumatology/kez020.
2
Eczematous changes on the hands--quiz case. Diagnosis: "Mechanic's hands" as part of the antisynthetase syndrome.手部湿疹样改变——病例分析。诊断:“机械工手”,为抗合成酶综合征的一部分。
Arch Dermatol. 2005 Jun;141(6):779-84. doi: 10.1001/archderm.141.6.779-c.
3
"Mechanic's hands": a misleading cutaneous sign of the antisynthetase syndrome.“机械工手”:抗合成酶综合征的一种误导性皮肤表现
Br J Dermatol. 2007 Jan;156(1):192-4. doi: 10.1111/j.1365-2133.2006.07593.x.
4
The Use of Methotrexate, Alone or in Combination With Other Therapies, for the Treatment of Palmoplantar Psoriasis.甲氨蝶呤单独或与其他疗法联合用于治疗掌跖银屑病
J Drugs Dermatol. 2015 Aug;14(8):888-92.
5
A histopathologic study of mechanic's hands associated with dermatomyositis: a report of five cases.机械工人手与皮肌炎相关的组织病理学研究:五例报告。
Int J Dermatol. 2009 Nov;48(11):1177-82. doi: 10.1111/j.1365-4632.2009.04164.x.
6
[Mechanic's hands: a characteristic cutaneous sign of antisynthetase syndrome].[机械工之手:抗合成酶综合征的特征性皮肤表现]
Actas Dermosifiliogr. 2005 May;96(4):241-4. doi: 10.1016/s0001-7310(05)73077-5.
7
["Mechanic's hands" during antisynthetase syndrome: a marker of systemic involvement?].抗合成酶综合征中的“机械工手”:全身受累的标志物?
Ann Dermatol Venereol. 2015 Mar;142(3):189-92. doi: 10.1016/j.annder.2014.11.003. Epub 2015 Jan 22.
8
Antisynthetase Syndrome and Autoantibodies: A Literature Review and Report of 4 Cases.抗合成酶综合征与自身抗体:文献综述及4例报告
Am J Case Rep. 2019 Jul 25;20:1094-1103. doi: 10.12659/AJCR.916178.
9
Successful response of refractory type I adult-onset pityriasis rubra pilaris with ustekinumab and acitretin combination therapy.乌司奴单抗与阿维A联合治疗难治性成人型Ⅰ型毛发红糠疹取得成功
J Dermatol. 2015 Aug;42(8):830-1. doi: 10.1111/1346-8138.12927. Epub 2015 May 18.
10
Antisynthetase syndrome: not just an inflammatory myopathy.抗合成酶综合征:不仅仅是一种炎症性肌病。
Cleve Clin J Med. 2013 Oct;80(10):655-66. doi: 10.3949/ccjm.80a.12171.

引用本文的文献

1
Clinical features and therapeutic challenges of psoriatic arthritis coexisting with antisynthetase syndrome: a case report and literature review.银屑病关节炎合并抗合成酶综合征的临床特征及治疗挑战:一例报告并文献复习
Front Immunol. 2025 Aug 8;16:1626226. doi: 10.3389/fimmu.2025.1626226. eCollection 2025.
2
A comprehensive review of dermatomyositis treatments - from rediscovered classics to promising horizons.皮肌炎治疗的全面综述——从重新发现的经典疗法到充满希望的新领域。
Expert Rev Clin Immunol. 2024 Feb;20(2):197-209. doi: 10.1080/1744666X.2023.2270737. Epub 2024 Jan 21.
3
Phase 3, multicentre, randomised, double-blind, placebo-controlled, parallel-group study of ustekinumab in Japanese patients with active polymyositis and dermatomyositis who have not adequately responded to one or more standard-of-care treatments.一项针对未充分应答一种或多种标准治疗的活动性多发性肌炎和皮肌炎的日本患者的乌司奴单抗的 3 期、多中心、随机、双盲、安慰剂对照、平行组研究。
RMD Open. 2023 Aug;9(3). doi: 10.1136/rmdopen-2023-003268.
4
A glance into the future of myositis therapy.肌炎治疗的未来展望。
Ther Adv Musculoskelet Dis. 2022 May 24;14:1759720X221100299. doi: 10.1177/1759720X221100299. eCollection 2022.
5
Mechanic's hand; is it a prodromic sign of disease relapse of anti-synthetase syndrome; a case report.技工手;它是抗合成酶综合征疾病复发的前驱症状吗?一例病例报告。
BMC Rheumatol. 2021 Jul 26;5(1):25. doi: 10.1186/s41927-021-00195-2.
6
Cutaneous Manifestations in Biological-Treated Inflammatory Bowel Disease Patients: A Narrative Review.生物治疗的炎症性肠病患者的皮肤表现:一项叙述性综述。
J Clin Med. 2021 Mar 3;10(5):1040. doi: 10.3390/jcm10051040.
7
Psoriasis and Connective Tissue Diseases.银屑病与结缔组织病。
Int J Mol Sci. 2020 Aug 13;21(16):5803. doi: 10.3390/ijms21165803.

本文引用的文献

1
A longitudinal cohort study of the anti-synthetase syndrome: increased severity of interstitial lung disease in black patients and patients with anti-PL7 and anti-PL12 autoantibodies.抗合成酶综合征的纵向队列研究:黑人患者以及抗PL7和抗PL12自身抗体患者间质性肺疾病严重程度增加
Rheumatology (Oxford). 2017 Jun 1;56(6):999-1007. doi: 10.1093/rheumatology/kex021.
2
Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease.乌司奴单抗诱导和维持治疗克罗恩病。
N Engl J Med. 2016 Nov 17;375(20):1946-1960. doi: 10.1056/NEJMoa1602773.
3
Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up.乌司奴单抗治疗中重度斑块状银屑病患者的长期安全性:5 年随访的最终结果。
Br J Dermatol. 2013 Apr;168(4):844-54. doi: 10.1111/bjd.12214.
4
A histopathologic study of mechanic's hands associated with dermatomyositis: a report of five cases.机械工人手与皮肌炎相关的组织病理学研究:五例报告。
Int J Dermatol. 2009 Nov;48(11):1177-82. doi: 10.1111/j.1365-4632.2009.04164.x.
5
Psoriasis.银屑病
N Engl J Med. 2009 Jul 30;361(5):496-509. doi: 10.1056/NEJMra0804595.

Successful treatment of refractory mechanic's hands with ustekinumab in a patient with the antisynthetase syndrome.

作者信息

Pinal-Fernandez Iago, Kroodsma Christopher T, Mammen Andrew L

机构信息

Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda.

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

Rheumatology (Oxford). 2019 Jul 1;58(7):1307-1308. doi: 10.1093/rheumatology/kez020.

DOI:10.1093/rheumatology/kez020
PMID:30793759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6821353/
Abstract
摘要