永生不死：调整翻译控制以调节寿命。
Vive ut Numquam Moriturus: Tweaking Translational Control to Regulate Longevity.
机构信息
Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
出版信息
Mol Cell. 2019 Feb 21;73(4):643-644. doi: 10.1016/j.molcel.2019.02.006.
PMID:30794792
Abstract
Molecular mechanisms regulating aging at the post-transcriptional level are not clear. In this issue of Molecular Cell,D'Amico et al. (2019) demonstrate that the translational inhibition of mitochondrial fission factor (MFF) regulates cellular homeostasis and aging.
摘要
调控转录后水平衰老的分子机制尚不清楚。在本期《分子细胞》中，D'Amico 等人（2019）证明了线粒体分裂因子（MFF）的翻译抑制作用可调节细胞内稳态和衰老。
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