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用于高灵敏度气载纳米颗粒检测的微型自读出共振悬臂梁和集成静电微通道分离器的策略。

Strategy toward Miniaturized, Self-out-Readable Resonant Cantilever and Integrated Electrostatic Microchannel Separator for Highly Sensitive Airborne Nanoparticle Detection.

机构信息

Institute of Semiconductor Technology (IHT), Technische Universität Braunschweig, Hans-Sommer-Str. 66, 38106 Braunschweig, Germany.

Laboratory for Emerging Nanometrology (LENA), Technische Universität Braunschweig, Langer Kamp 6a, 38106 Braunschweig, Germany.

出版信息

Sensors (Basel). 2019 Feb 21;19(4):901. doi: 10.3390/s19040901.

DOI:10.3390/s19040901
PMID:30795547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6412668/
Abstract

In this paper, a self-out-readable, miniaturized cantilever resonator for highly sensitive airborne nanoparticle (NP) detection is presented. The cantilever, which is operated in the fundamental in-plane resonance mode, is used as a microbalance with femtogram resolution. To maximize sensitivity and read-out signal amplitude of the piezo-resistive Wheatstone half bridge, the geometric parameters of the sensor design are optimized by finite element modelling (FEM). The electrical read-out of the cantilever movement is realized by piezo-resistive struts at the sides of the cantilever resonator that enable real-time tracking using a phase-locked loop (PLL) circuit. Cantilevers with minimum resonator mass of 1.72 ng and resonance frequency of ~440 kHz were fabricated, providing a theoretical sensitivity of 7.8 fg/Hz. In addition, for electrostatic NP collection, the cantilever has a negative-biased electrode located at its free end. Moreover, the counter-electrode surrounding the cantilever and a µ-channel, guiding the particle-laden air flow towards the cantilever, are integrated with the sensor chip. µ-channels and varying sampling voltages will also be used to accomplish particle separation for size-selective NP detection. To sum up, the presented airborne NP sensor is expected to demonstrate significant improvements in the field of handheld, micro-/nanoelectromechanical systems (M/NEMS)-based NP monitoring devices.

摘要

本文提出了一种自读式、微型悬臂谐振器,用于高灵敏度的空气中纳米颗粒(NP)检测。该悬臂采用基本的面内共振模式工作,作为具有飞克分辨率的微天平使用。为了最大限度地提高压阻式惠斯通电桥的灵敏度和读出信号幅度,通过有限元建模(FEM)对传感器设计的几何参数进行了优化。通过位于悬臂谐振器两侧的压阻支柱实现悬臂运动的电读出,这使得可以使用锁相环(PLL)电路实时跟踪。制造了具有最小谐振器质量为 1.72ng 和共振频率约为 440kHz 的悬臂,提供了 7.8fg/Hz 的理论灵敏度。此外,为了进行静电 NP 收集,悬臂在自由端具有负偏置电极。此外,围绕悬臂的对电极和引导载有颗粒的空气流向悬臂的微通道与传感器芯片集成在一起。微通道和变化的采样电压也将用于实现用于尺寸选择性 NP 检测的颗粒分离。总之,所提出的空气中 NP 传感器有望在手持式、微/纳机电系统(M/NEMS)基 NP 监测设备领域取得显著进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/b703a86b869e/sensors-19-00901-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/0398a7d22241/sensors-19-00901-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/e68841dcb477/sensors-19-00901-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/0782a54d5f0b/sensors-19-00901-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/34ca71a4ffc6/sensors-19-00901-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/8eb5e684000c/sensors-19-00901-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/cc0a0e63155d/sensors-19-00901-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/25764b8761b7/sensors-19-00901-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/2cf522b99204/sensors-19-00901-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/b3ae152a7022/sensors-19-00901-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/b703a86b869e/sensors-19-00901-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/0398a7d22241/sensors-19-00901-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/e68841dcb477/sensors-19-00901-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/0782a54d5f0b/sensors-19-00901-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/34ca71a4ffc6/sensors-19-00901-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/8eb5e684000c/sensors-19-00901-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/cc0a0e63155d/sensors-19-00901-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/25764b8761b7/sensors-19-00901-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/2cf522b99204/sensors-19-00901-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/b3ae152a7022/sensors-19-00901-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e9/6412668/b703a86b869e/sensors-19-00901-g010.jpg

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