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精准医疗:推进症状和自我管理科学。

Precision health: Advancing symptom and self-management science.

机构信息

Cardiac Electrophysiology, Columbia University School of Nursing, Columbia University Medical Center, New York, NY.

School of Nursing and Department of Biomedical Informatics, Columbia University, New York, NY.

出版信息

Nurs Outlook. 2019 Jul-Aug;67(4):462-475. doi: 10.1016/j.outlook.2019.01.003. Epub 2019 Jan 18.

DOI:10.1016/j.outlook.2019.01.003
PMID:30795850
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6688754/
Abstract

BACKGROUND

Precision health considers individual lifestyle, genetics, behaviors, and environment context and facilitates interventions aimed at helping individuals achieve well-being and optimal health.

PURPOSE

To present the Nursing Science Precision Health (NSPH) Model and describe the integration of precision health concepts within the domains of symptom and self-management science as reflected in the National Institute of Nursing Research P30 Centers of Excellence and P20 Exploratory Centers.

METHODS

Center members developed the NSPH Model and the manuscript based on presentations and discussions at the annual NINR Center Directors Meeting and in follow-up telephone meetings.

DISCUSSION

The NSPH Model comprises four precision components (measurement; characterization of phenotype including lifestyle and environment; characterization of genotype and other biomarkers; and intervention target discovery, design, and delivery) that are underpinned by an information and data science infrastructure.

CONCLUSION

Nurse scientist leadership is necessary to realize the vision of precision health as reflected in the NSPH Model.

摘要

背景

精准健康考虑个体的生活方式、遗传、行为和环境背景,并促进旨在帮助个体实现健康和最佳健康的干预措施。

目的

介绍护理科学精准健康(NSPH)模型,并描述精准健康概念在症状和自我管理科学领域的整合,这反映在国立卫生研究院护理研究 P30 卓越中心和 P20 探索中心中。

方法

中心成员根据年度 NINR 中心主任会议上的演示和讨论以及后续电话会议,制定了 NSPH 模型和手稿。

讨论

NSPH 模型包括四个精准组件(测量;表型特征,包括生活方式和环境;基因型和其他生物标志物的特征;以及干预目标发现、设计和交付),这些组件由信息和数据科学基础设施支撑。

结论

护士科学家的领导力对于实现 NSPH 模型中反映的精准健康愿景是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df26/6688754/2f3369d40541/nihms-1033453-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df26/6688754/ebc3959cc071/nihms-1033453-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df26/6688754/2f3369d40541/nihms-1033453-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df26/6688754/ebc3959cc071/nihms-1033453-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df26/6688754/2f3369d40541/nihms-1033453-f0002.jpg

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