Kutzora S, Puerto Valencia L, Weber A, Huß J, Hendrowarsito L, Nennstiel-Ratzel U, Herr C, Heinze S
Department of Occupational and Environmental Health/Epidemiology, Bavarian Health and Food Safety Authority (LGL), Pfarrstr. 3, 80538 Munich, Germany.
Department of Occupational and Environmental Health/Epidemiology, Bavarian Health and Food Safety Authority (LGL), Pfarrstr. 3, 80538 Munich, Germany.
Allergol Immunopathol (Madr). 2019 Jul-Aug;47(4):386-400. doi: 10.1016/j.aller.2018.12.008. Epub 2019 Feb 21.
Asthma is the most common chronic disease in children, and associations with crowding have been reported. The aim of this study was to explore possible associations of crowding with asthma in children.
Seven cross-sectional surveys with preschool children were conducted within the framework of the health monitoring units in Bavaria, Germany, from 2004 to 2014. Residential crowding was defined as habitation of more than one person per room or less than 20m living space per person. Logistic regression models examined temporal changes in crowding, applying the first survey as reference. The relationship between crowding and physician-diagnosed asthma, asthma defined by the International Study of Asthma and Allergies in Childhood (ISAAC) and asthma symptoms were analyzed.
Analyzing temporal changes of crowding rates did not reveal any differences over the years. However, the stratified descriptive analysis indicated a crowding increase in time in urban households where parents had a low education level (47.9% in 2004/05, 55.8% in 2014/15). No association was found between crowding and the variables "physician-diagnosed asthma" in 2014/15, "asthma defined by ISAAC" in 2014/15, or "wheezing" in 2014/15. A positive association with cough was identified in 2014/15 after adjusting for confounders (aOR=1.42 [95% CI: 1.20-1.69]).
In general, residential crowding did not change from 2004 to 2014; however, there seems to be a small upsurge for children with low-educated parents, living in urban areas over the years. A statistically significant association between crowding and cough was only found in the survey from 2014/15.
哮喘是儿童最常见的慢性病,且已有研究报道其与居住拥挤空间拥挤有关。本研究旨在探讨居住拥挤与儿童哮喘之间可能存在的关联。
2004年至2014年期间,在德国巴伐利亚州健康监测单位的框架内,对学龄前儿童进行了七次横断面调查。居住拥挤定义为每个房间居住人数超过一人或人均居住面积小于20平方米。采用逻辑回归模型,以第一次调查为参照,分析居住拥挤情况随时间的变化。分析了居住拥挤与医生诊断的哮喘、儿童哮喘和过敏国际研究(ISAAC)定义的哮喘以及哮喘症状之间的关系。
分析居住拥挤率随时间的变化未发现多年间存在差异。然而,分层描述性分析表明,父母教育水平较低的城市家庭中,居住拥挤情况随时间有所增加(2004/05年为47.9%,2014/15年为55.8%)。2014/15年,未发现居住拥挤与“医生诊断的哮喘”、2014/15年ISAAC定义的“哮喘”或2014/15年“喘息”变量之间存在关联。在调整混杂因素后,2014/15年发现居住拥挤与咳嗽呈正相关(调整后比值比=1.42 [95%置信区间:1.20 - 1.69])。
总体而言,2004年至2014年居住拥挤情况未发生变化;然而,多年来,居住在城市地区、父母受教育程度较低的儿童中,居住拥挤情况似乎略有上升。仅在2014/15年的调查中发现居住拥挤与咳嗽之间存在统计学上的显著关联。