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J Allergy Clin Immunol. 2019 Sep;144(3):866-869.e4. doi: 10.1016/j.jaci.2019.05.025. Epub 2019 Jun 1.
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居住环境与高污染城区小学生自述呼吸道和哮喘症状的关系。

Residential environment in relation to self-report of respiratory and asthma symptoms among primary school children in a high-polluted urban area.

机构信息

Department of Health, Ministry of Public Health, Nonthaburi, 11000, Thailand.

Faculty of Public Health, Thammasat University (Rungsit Campus), Pathumthani, 12121, Thailand.

出版信息

Sci Rep. 2022 Feb 22;12(1):2946. doi: 10.1038/s41598-022-06919-9.

DOI:10.1038/s41598-022-06919-9
PMID:35194093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8863880/
Abstract

Respiratory disease and its complication are the cause of children deaths worldwide every year. Several epidemiological studies pointed out an association between quality of residential in inner city and risk of children health. However, few studies had been focused in high-polluted urban area in low to middle income countries. A cross-sectional study was conducted to investigate the association between residential environments and respiratory symptoms including asthma among 658 primary school children living in urban area of Bangkok Thailand. The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire was modified to access symptoms during the past 12 months. Binary logistic regression model was performed. Living near garment and clothing shop is associated with shortness of breath (AOR = 1.846; 95% CI 1.034, 3.297). Vectors in home is related to dry cough at night (AOR = 1.505; 95% CI 1.052, 2.153) and phlegm (AOR = 1.414; 95% CI 1.014, 1.973). Wall dampness is increased odd of having wheezing or whistling (asthma) in the chest (AOR = 1.921; 95% CI 1.141, 3.235). Children age, gender, and a family history of asthma were modified the associations. Our finding may provide strategies focusing on living environment improvement with a specific group of children to address respiratory disease prevention.

摘要

呼吸道疾病及其并发症是全球每年导致儿童死亡的原因。几项流行病学研究指出,内城居住质量与儿童健康风险之间存在关联。然而,在中低收入国家的高污染城市地区,很少有研究关注这一问题。本研究采用横断面设计,旨在调查泰国曼谷市城区居住环境与呼吸道症状(包括哮喘)之间的关系,共纳入 658 名小学生。使用国际儿童哮喘和过敏研究(ISAAC)问卷评估过去 12 个月的症状。采用二元逻辑回归模型进行分析。居住在制衣店附近与呼吸急促有关(比值比(OR)=1.846;95%可信区间(CI)为 1.0343.297)。家中有臭虫与夜间干咳(OR=1.505;95%CI 为 1.0522.153)和咳痰(OR=1.414;95%CI 为 1.0141.973)有关。墙壁潮湿增加了胸部有哮鸣音或喘息(哮喘)的几率(比值比(OR)=1.921;95%CI 为 1.1413.235)。儿童年龄、性别和哮喘家族史会改变这些关联。我们的研究结果为改善居住环境提供了策略,针对特定儿童群体以预防呼吸道疾病。