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[皮质类固醇眼药水在儿童过敏性眼病中的应用]

[Application of corticosteroid eye drops for allergic eye diseases in children].

作者信息

Csorba Anita, Soproni Anna, Maneschg Otto, Nagy Zoltán Zsolt, Szamosi Anna

机构信息

Szemészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Mária u. 39., 1085.

Soproni Anna Szemészeti Magánrendelő Budapest.

出版信息

Orv Hetil. 2019 Mar;160(9):329-337. doi: 10.1556/650.2019.31265.

DOI:10.1556/650.2019.31265
PMID:30798620
Abstract

The prevalence of allergic diseases has been increasing recently. Allergy has various symptoms. Allergic eye diseases (seasonal and perennial allergic conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, giant papillary conjunctivitis, contact blepharoconjunctivitis) are common in atopic patients. Treatment options for allergic conjunctivitis include local and systemic antihistamines, mast cell stabilizers, dual-action agents, vasoconstrictors and corticosteroids. Treatment seems easy, but inappropriate therapy - in extreme cases - can lead to vision loss. Corticosteroid eyedrops provide effective relief of symptoms, however, their use is limited due to their severe side effects. Both steroid-induced cataract and steroid-induced glaucoma are dangerous for vision. The characteristics, frequency and risks of these side effects have been studied widely in adults, but there are very few studies focused on children. According to the present studies, the side effects of topically administered corticosteroids appear more often in children than in adults. Orv Hetil. 2019; 160(9): 329-337.

摘要

近年来,过敏性疾病的患病率一直在上升。过敏有多种症状。过敏性眼病(季节性和常年性过敏性结膜炎、春季角结膜炎、特应性角结膜炎、巨乳头性结膜炎、接触性睑结膜炎)在特应性患者中很常见。过敏性结膜炎的治疗选择包括局部和全身用抗组胺药、肥大细胞稳定剂、双重作用药物、血管收缩剂和皮质类固醇。治疗看似简单,但在极端情况下,不恰当的治疗可能导致视力丧失。皮质类固醇眼药水能有效缓解症状,然而,由于其严重的副作用,其使用受到限制。类固醇性白内障和类固醇性青光眼都对视力有危害。这些副作用的特征、发生率和风险在成年人中已得到广泛研究,但针对儿童的研究却很少。根据目前的研究,局部应用皮质类固醇的副作用在儿童中比在成年人中更常见。《匈牙利医学周报》。2019年;160(9): 329 - 337。

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[Application of corticosteroid eye drops for allergic eye diseases in children].[皮质类固醇眼药水在儿童过敏性眼病中的应用]
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Allergic ocular disorders: a spectrum of diseases.过敏性眼部疾病:一系列病症。
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[Seasonal and Perennial Allergic Rhinoconjunctivitis].[季节性和常年性变应性鼻结膜炎]
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