Jackson Daniel, Huang Meng, Fernando Harshica, Ansari Ghulam, Howarth Marilyn, Mesaros Clementina, Penning Trevor, Elferink Cornelis
1 Department of Pharmacology and Toxicology, The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
2 Center of Excellence in Environmental Toxicology, Perelman School of Medicine, Philadelphia, PA, USA.
New Solut. 2019 Feb;28(4):599-616. doi: 10.1177/1048291118815606.
This article provides a description of the rationale and processes adopted by the Gulf Coast Health Alliance: Health Risks related to the Macondo Spill consortium to evaluate and communicate the risk of exposure to polycyclic aromatic hydrocarbons (PAHs) in seafood over several years following the Deepwater Horizon disaster and subsequent oil spill. We examined gaps in knowledge associated with PAH toxicity following exposure to petrogenic (oil-derived) PAHs by studying the metabolic fate of PAHs and their potential toxicity using sophisticated analytical methods. Using the data generated, we developed a risk communication strategy designed to meet the needs of the stakeholder communities including a consumption guideline calculator, a web-based tool to reconcile seafood consumption with risk of adverse health effects.
马孔多漏油事件相关健康风险联盟所采用的基本原理和流程，该联盟旨在评估并传达“深水地平线”灾难及随后的石油泄漏事件发生后的数年里，海产品中多环芳烃（PAHs）暴露风险。我们通过运用精密分析方法研究多环芳烃的代谢归宿及其潜在毒性，审视了与接触源自石油的成岩多环芳烃后多环芳烃毒性相关的知识空白。利用所生成的数据，我们制定了一项风险沟通策略，以满足利益相关者群体的需求，其中包括一个消费指南计算器，这是一个基于网络的工具，用于协调海产品消费与不良健康影响风险。
