Department of Ophthalmology (H.D.), Cankaya Medical Center, Izmir, Turkey; and Department of Ophthalmology (C.K.), Derince Training and Research Hospital, Kocaeli, Turkey.
Eye Contact Lens. 2019 Nov;45(6):390-393. doi: 10.1097/ICL.0000000000000586.
To investigate the effects of contact lens (CL) on the frequency of pinguecula, and the relationship between dry eye disease and pinguecula.
Two hundred and 33 cases of soft CL wearers and 230 age-matched nonwearers were enrolled in the study. Schirmer I test (ST) scores and tear break-up time (TBUT) were determined in all participants. A questionnaire including ocular surface disease index (OSDI), age, sex, and duration of CL wear was implemented to the participants before the examination.
The prevalence of pinguecula was 27.8% (n: 65) in the CL group and 26.5% (n: 61) in the control group. There was no significant difference between the groups (P=0.841). The prevalence of pinguecula increased with age in both groups. There was no significant difference in the prevalence of pinguecula when users were divided into three groups according to the duration of CL wear (P=0.575). The TBUT scores were lower, and the OSDI scores were higher in the CL group. The TBUT scores were lower in patients with pinguecula in both groups. The OSDI scores were higher in the CL group. There was no significant difference regarding the OSDI scores between patients with pinguecula and healthy participants in the CL group; however, OSDI scores were significantly higher in patients with pinguecula in control group. There were no significant differences in the ST scores between the groups, and between patients with pinguecula and healthy participants.
This is the second study that evaluates the effects of soft CL wearing on pinguecula prevalence. We found that CL wearing does not affect the prevalence of pinguecula. Considering the OSDI scores in patients with pinguecula in the CL group, CL may suppress the irritant symptoms of pinguecula.
探讨隐形眼镜（CL）对胬肉发病率的影响，以及干眼症与胬肉的关系。
本研究纳入了 203 例软 CL 佩戴者和 230 例年龄匹配的非佩戴者。所有参与者均接受 Schirmer I 试验（ST）评分和泪膜破裂时间（TBUT）检查。在检查前，向参与者发放包括眼表疾病指数（OSDI）、年龄、性别和 CL 佩戴时间的问卷。
CL 组胬肉的患病率为 27.8%（n：65），对照组为 26.5%（n：61）。两组间无显著性差异（P=0.841）。两组中胬肉的患病率均随年龄增长而增加。根据 CL 佩戴时间将使用者分为三组，胬肉的患病率无显著差异（P=0.575）。CL 组的 TBUT 评分较低，OSDI 评分较高。两组中胬肉患者的 TBUT 评分均较低。CL 组中胬肉患者的 OSDI 评分较高。CL 组中胬肉患者的 OSDI 评分与健康参与者无显著差异；然而，对照组中胬肉患者的 OSDI 评分明显更高。两组间 ST 评分以及胬肉患者与健康参与者间 ST 评分均无显著差异。
这是第二项评估软 CL 佩戴对胬肉患病率影响的研究。我们发现 CL 佩戴不会影响胬肉的患病率。考虑到 CL 组中胬肉患者的 OSDI 评分，CL 可能抑制了胬肉的刺激症状。
