Jammal Hisham M, Abu-Ameerh Mohammed, Hiasat Jamila G, Issa Sara, Al Bdour Muawyah
Department of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Department of Ophthalmology, Jordan University Hospital, The University of Jordan, Amman, Jordan.
J Ophthalmol. 2023 Feb 28;2023:9060495. doi: 10.1155/2023/9060495. eCollection 2023.
To assess the relationship between diabetes mellitus (DM) and the presence of pinguecula and to identify other risk factors associated with pinguecula in patients attending the eye clinic at two tertiary university hospitals in Jordan.
This was a comparative cross-sectional hospital-based study of 241 consecutive patients (122 patients with DM and 119 patients with no diabetes). All patients underwent complete ophthalmic examination, and data were collected regarding age, sex, occupational activity, presence and grade of pinguecula, glycosylated hemoglobin (HbA1c), and presence of diabetic retinopathy.
The mean (standard deviation, SD) ages of the DM and non-DM groups were 59.5 (10.8) years and 59.0 (11.6) years (-value = 0.729), respectively. There was no significant difference in the prevalence of pinguecula between the diabetic and nondiabetic groups (66.4% vs. 66.5%, = 0.998). Multivariate logistic regression analysis revealed that only outdoor occupational activity (OR = 5.16, 95% CI: 1.98-13.44, = 0.001) was associated with increased prevalence of pinguecula. DM was not significantly associated with pinguecula (OR = 0.96, 95% confidence interval (CI): 0.55-1.67, = 0.873). Neither age nor sex were significantly associated with pinguecula (-value = 0.808, -value = 0.390), respectively.
DM was not significantly associated with the development of pinguecula in this Jordanian population. The prevalence of pinguecula was significantly associated with an outdoor occupational activity.
评估糖尿病（DM）与睑裂斑存在之间的关系，并确定约旦两家三级大学医院眼科门诊患者中与睑裂斑相关的其他危险因素。
这是一项基于医院的比较性横断面研究，共纳入241例连续患者（122例糖尿病患者和119例非糖尿病患者）。所有患者均接受了全面的眼科检查，并收集了有关年龄、性别、职业活动、睑裂斑的存在及分级、糖化血红蛋白（HbA1c）以及糖尿病视网膜病变的存在情况的数据。
糖尿病组和非糖尿病组的平均（标准差，SD）年龄分别为59.5（10.8）岁和59.0（11.6）岁（P值 = 0.729）。糖尿病组和非糖尿病组睑裂斑的患病率无显著差异（66.4%对66.5%，P = 0.998）。多因素逻辑回归分析显示，只有户外职业活动（比值比[OR] = 5.16，95%可信区间[CI]：1.98 - 13.44，P = 0.001）与睑裂斑患病率增加相关。糖尿病与睑裂斑无显著关联（OR = 0.96，95%可信区间[CI]：0.55 - 1.67，P = 0.873）。年龄和性别与睑裂斑均无显著关联（P值分别为0.808和0.390）。
在这一约旦人群中，糖尿病与睑裂斑的发生无显著关联。睑裂斑的患病率与户外职业活动显著相关。
