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高血压治疗能否解释中风死亡率的下降?

Does treatment of hypertension explain the decline in mortality from stroke?

作者信息

Bonita R, Beaglehole R

出版信息

Br Med J (Clin Res Ed). 1986 Jan 18;292(6514):191-2. doi: 10.1136/bmj.292.6514.191.

Abstract

Mortality from stroke has been declining in New Zealand since 1950 and at an accelerating rate since the early 1970s. Hypertension is the single most important risk factor for stroke. The temporal association between the recent decline in mortality and an increase in the proportion of patients with hypertension detected and treated led to the assumption of a cause and effect relation. Data from studies of the prevalence of blood pressure carried out in the community and from therapeutic trials of the treatment of hypertension were used to estimate the proportion of the decline in mortality from stroke that could be accounted for by increased treatment of hypertension during 1973-82 in New Zealand. Treatment of hypertension was estimated to account for roughly 10% of the observed reduction in deaths from stroke. Greater understanding of the reasons for the decline in mortality from stroke is required.

摘要

自1950年以来,新西兰中风死亡率一直在下降,自20世纪70年代初以来下降速度加快。高血压是中风最重要的单一危险因素。近期死亡率下降与检测和治疗的高血压患者比例增加之间的时间关联导致了因果关系的假设。利用社区进行的血压患病率研究数据和高血压治疗的临床试验数据,估计了1973 - 1982年期间新西兰因高血压治疗增加而导致的中风死亡率下降比例。据估计,高血压治疗约占观察到的中风死亡减少的10%。需要更深入了解中风死亡率下降的原因。

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