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脑肿瘤检测与分类:基于标记的分水岭算法和多级优先级特征选择框架

Brain tumor detection and classification: A framework of marker-based watershed algorithm and multilevel priority features selection.

作者信息

Khan Muhammad A, Lali Ikram U, Rehman Amjad, Ishaq Mubashar, Sharif Muhammad, Saba Tanzila, Zahoor Saliha, Akram Tallha

机构信息

Department of Computer Science and Engineering, HITEC University Museum Road, Taxila, Pakistan.

Department of Computer Science, University of Gujrat, Gujrat, Pakistan.

出版信息

Microsc Res Tech. 2019 Jun;82(6):909-922. doi: 10.1002/jemt.23238. Epub 2019 Feb 23.

DOI:10.1002/jemt.23238
PMID:30801840
Abstract

Brain tumor identification using magnetic resonance images (MRI) is an important research domain in the field of medical imaging. Use of computerized techniques helps the doctors for the diagnosis and treatment against brain cancer. In this article, an automated system is developed for tumor extraction and classification from MRI. It is based on marker-based watershed segmentation and features selection. Five primary steps are involved in the proposed system including tumor contrast, tumor extraction, multimodel features extraction, features selection, and classification. A gamma contrast stretching approach is implemented to improve the contrast of a tumor. Then, segmentation is done using marker-based watershed algorithm. Shape, texture, and point features are extracted in the next step and high ranked 70% features are only selected through chi-square max conditional priority features approach. In the later step, selected features are fused using a serial-based concatenation method before classifying using support vector machine. All the experiments are performed on three data sets including Harvard, BRATS 2013, and privately collected MR images data set. Simulation results clearly reveal that the proposed system outperforms existing methods with greater precision and accuracy.

摘要

利用磁共振成像(MRI)识别脑肿瘤是医学成像领域的一个重要研究方向。计算机技术的应用有助于医生对脑癌进行诊断和治疗。本文开发了一种用于从MRI中提取和分类肿瘤的自动化系统。该系统基于基于标记的分水岭分割和特征选择。所提出的系统涉及五个主要步骤,包括肿瘤对比度增强、肿瘤提取、多模态特征提取、特征选择和分类。采用伽马对比度拉伸方法来提高肿瘤的对比度。然后,使用基于标记的分水岭算法进行分割。下一步提取形状、纹理和点特征,并仅通过卡方最大条件优先级特征方法选择排名前70%的特征。在后续步骤中,在使用支持向量机进行分类之前,使用基于序列的串联方法融合所选特征。所有实验均在包括哈佛数据集、BRATS 2013数据集和私人收集的MR图像数据集在内的三个数据集上进行。仿真结果清楚地表明,所提出的系统在精度和准确性方面优于现有方法。

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