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一种使用图像增强和混合特征进行体内人脑肿瘤检测的框架。

A framework for in-vivo human brain tumor detection using image augmentation and hybrid features.

作者信息

Jha Manika, Gupta Richa, Saxena Rajiv

机构信息

Department of Electronics and Communication, Jaypee Institute of Information Technology, Noida, 201309 India.

出版信息

Health Inf Sci Syst. 2022 Aug 27;10(1):23. doi: 10.1007/s13755-022-00193-9. eCollection 2022 Dec.

DOI:10.1007/s13755-022-00193-9
PMID:36042871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9420164/
Abstract

Brain tumor is caused by the uncontrolled and accelerated multiplication of cells in the brain. If not treated early enough, it can lead to death. Despite multiple significant efforts and promising research outcomes, accurate segmentation and classification of tumors remain a challenge. The changes in tumor location, shape, and size make brain tumor identification extremely difficult. An Extreme Gradient Boosting (XGBoost) algorithm using is proposed in this work to classify four subtypes of brain tumor-normal, gliomas, meningiomas, and pituitary tumors. Because the dataset was limited in size, image augmentation using a conditional Generative Adversarial Network (cGAN) was used to expand the training data. Deep features, Two-Dimensional Fractional Fourier Transform (2D-FrFT) features, and geometric features are fused together to extract both global and local information from the Magnetic Resonance Imaging (MRI) scans. The model attained enhanced performance with a classification accuracy of 98.79% and sensitivity of 98.77% for the test images. In comparison to state-of-the-art algorithms employing the Kaggle brain tumor dataset, the suggested model showed a considerable improvement. The improved results show the prominence of feature fusion and establish XGBoost as an appropriate classifier for brain tumor detection in terms on testing accuracy, sensitivity and Area under receiver operating characteristic (AUROC) curve.

摘要

脑肿瘤是由大脑中细胞不受控制地加速增殖引起的。如果不及早治疗,可能会导致死亡。尽管付出了诸多巨大努力并取得了有前景的研究成果,但肿瘤的精确分割和分类仍然是一项挑战。肿瘤位置、形状和大小的变化使得脑肿瘤识别极其困难。本文提出了一种使用极端梯度提升(XGBoost)算法对脑肿瘤的四种亚型——正常、胶质瘤、脑膜瘤和垂体瘤进行分类。由于数据集规模有限,使用条件生成对抗网络(cGAN)进行图像增强以扩充训练数据。将深度特征、二维分数傅里叶变换(2D-FrFT)特征和几何特征融合在一起,从磁共振成像(MRI)扫描中提取全局和局部信息。该模型在测试图像上实现了增强的性能,分类准确率为98.79%,灵敏度为98.77%。与使用Kaggle脑肿瘤数据集的现有算法相比,所提出的模型有显著改进。改进结果表明了特征融合的重要性,并在测试准确率、灵敏度和受试者工作特征曲线下面积(AUROC)方面确立了XGBoost作为脑肿瘤检测的合适分类器。

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