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股骨粗隆间骨折围手术期隐性失血的动态分析

Dynamic Analysis of Perioperative Hidden Blood Loss in Intertrochanteric Fractures.

作者信息

Tian Shuwei, Li Hui, Liu Meiyu, Zhang Yanlong, Peng Aqin

机构信息

1 Hebei Provincial General Hospital, Shijiazhuang, Hebei, China.

2 Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

出版信息

Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029618823279. doi: 10.1177/1076029618823279.

Abstract

To analyze the dynamic variation in perioperative hidden blood loss in patients with intertrochanteric fracture. From January to December 2017, 79 patients with intertrochanteric fracture were treated with proximal femoral nail antirotation. Serial complete blood count assays were performed consecutively in the 3 days after admission, on the day of surgery, and 7 days postoperatively. Blood loss during surgery, postoperative drainage, and perioperative blood transfusion volumes were recorded. Dynamic changes in hemoglobin (Hb) prior to surgery were recorded and compared between males and females. Patients were divided into the no blood transfusion group, the 400-mL blood transfusion group, and the 800-mL blood transfusion group depending on the volume of perioperative blood transfusion. Total and hidden blood loss were separately calculated according to the Gross equation. Lowest mean Hb values occurred on day 2 after admission among men (104.8 g/L) and on day 3 after admission among women (98.6 g/L). The average Hb decrease was 11.4 g/L, 11.8 g/L, and 8.9 g/L in the no, 400-mL, and 800-mL blood transfusion groups, respectively. The lowest Hb value occurred on postoperative day 2. Hemoglobin increased on postoperative day 3 and stabilized by day 6. In the no blood transfusion group, the average total blood loss was 406.0 ± 255.6 mL, 628.3 ± 267.2 mL, and 759.7 ± 322.1 mL in the no blood transfusion, 400-mL blood transfusion, and 800-mL blood transfusion groups, respectively, and hidden blood loss was 326.0 ± 246.6 mL, 512.1 ± 247.3 mL, and 596.1 ± 306.9 mL, respectively. Perioperative hidden blood loss occurred prior to surgery for intertrochanteric fracture and ended on postoperative day 2.

摘要

分析股骨转子间骨折患者围手术期隐性失血的动态变化。2017年1月至12月,79例股骨转子间骨折患者接受股骨近端抗旋髓内钉治疗。入院后3天内、手术当天及术后7天连续进行血常规检测。记录手术中的失血量、术后引流量及围手术期输血量。记录术前血红蛋白(Hb)的动态变化,并比较男性和女性之间的差异。根据围手术期输血量将患者分为未输血组、400 mL输血组和800 mL输血组。根据Gross公式分别计算总失血量和隐性失血量。男性入院后第2天Hb均值最低(104.8 g/L),女性入院后第3天Hb均值最低(98.6 g/L)。未输血组、400 mL输血组和800 mL输血组的Hb平均下降分别为11.4 g/L、11.8 g/L和8.9 g/L。最低Hb值出现在术后第2天。术后第3天Hb升高,第6天稳定。未输血组中,未输血、400 mL输血和800 mL输血组的平均总失血量分别为406.0±255.6 mL、628.3±267.2 mL和759.7±322.1 mL,隐性失血量分别为326.0±246.6 mL、512.1±247.3 mL和596.1±306.9 mL。股骨转子间骨折围手术期隐性失血发生在术前,术后第2天结束。

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