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促性腺激素诱导排卵后的男女比例。

Male to female ratio after gonadotropin-induced ovulation.

作者信息

Ben-Rafael Z, Matalon A, Blankstein J, Serr D M, Lunenfeld B, Mashiach S

出版信息

Fertil Steril. 1986 Jan;45(1):36-40. doi: 10.1016/s0015-0282(16)49093-x.

DOI:10.1016/s0015-0282(16)49093-x
PMID:3080345
Abstract

Two hundred fifty-six children were born in 195 births from 176 women that conceived after human menopausal gonadotropin/human chorionic gonadotropin (hMG/hCG)-induced ovulation. The secondary sex ratio was 50% male to 50% female births, which is not statistically different from the Israeli or Occidental population. The same trend was observed for single births and for twins. Thus, the data presented do not support the reports of increased numbers of female infants in those conceived after induction of ovulation. Factors that are expected to have been shown to affect sex ratio: maternal age at delivery, total number of ampules of hMG/hCG administered in the conceptional cycle, urinary estrogen levels on the day of hCG injection, degree of ovarian hyperstimulation syndrome, and time of insemination in relation to the basal body temperature rise were found to be insignificant. Thus, the hypothesis that a local hormonal environment (gonadotropin or estrogen levels) during hMG/hCG treatment possibly affects sex selection was not confirmed.

摘要

176名女性在接受人绝经期促性腺激素/人绒毛膜促性腺激素(hMG/hCG)诱导排卵后怀孕,共分娩195次,产下256名婴儿。第二性比为男婴与女婴各占50%,与以色列或西方人群无统计学差异。单胎和双胎情况也呈现相同趋势。因此,本文所呈现的数据并不支持有关诱导排卵后受孕所生女性婴儿数量增加的报道。预期已被证明会影响性比的因素:分娩时的母亲年龄、受孕周期中注射hMG/hCG的安瓿总数、注射hCG当天的尿雌激素水平、卵巢过度刺激综合征的程度以及与基础体温上升相关的授精时间,均无显著意义。因此,关于hMG/hCG治疗期间局部激素环境(促性腺激素或雌激素水平)可能影响性别选择的假设未得到证实。

相似文献

1
Male to female ratio after gonadotropin-induced ovulation.促性腺激素诱导排卵后的男女比例。
Fertil Steril. 1986 Jan;45(1):36-40. doi: 10.1016/s0015-0282(16)49093-x.
2
Induction of ovulation and pregnancy in twenty-six patients with primary hypogonadotropic amenorrhea.26例原发性低促性腺激素性闭经患者的促排卵及妊娠诱导
Int J Fertil. 1980;25(4):257-66.
3
Induction of ovulation with combined human gonadotropins and dexamethasone in women with polycystic ovarian disease.
Fertil Steril. 1983 Aug;40(2):183-6. doi: 10.1016/s0015-0282(16)47234-1.
4
Sequential use of clomiphene citrate and human menopausal gonadotropin in ovulation induction.枸橼酸氯米芬与人绝经期促性腺激素序贯用于促排卵。
Fertil Steril. 1976 Jan;27(1):72-82. doi: 10.1016/s0015-0282(16)41597-9.
5
[The treatment of sterility with human gonadotropins. (HMG-HCG)].
Patol Clin Ostet Ginecol. 1973;1(3):108-17.
6
The use of human gonadotropins for the induction of ovulation in women with polycystic ovarian disease.
Fertil Steril. 1980 May;33(5):479-86. doi: 10.1016/s0015-0282(16)44711-4.
7
Successful pregnancies in patients with estrogenic anovulation after low-dose human chorionic gonadotropin therapy alone following hMG for controlled ovarian hyperstimulation.在使用人绝经期促性腺激素(hMG)进行控制性卵巢过度刺激后,仅接受低剂量人绒毛膜促性腺激素治疗的雌激素性无排卵患者成功妊娠。
J Assist Reprod Genet. 2005 Jan;22(1):37-40. doi: 10.1007/s10815-005-0819-7.
8
[A simplified quick semi-quantitative determination of urinary estrogen in non-pregnant female: the application for monitoring of follicular maturation at HMG-HCG therapy].
Nihon Sanka Fujinka Gakkai Zasshi. 1986 Jan;38(1):64-72.
9
Ovulation induction with human menopausal gonadotrophins: an evaluation of a variable daily dosage regimen.
Int J Fertil. 1977;22(4):225-31.
10
Observations on 320 infertile patients treated with human gonadotropins (human menopausal gonadotropin/human chorionic gonadotropin).对320例接受人促性腺激素(人绝经期促性腺激素/人绒毛膜促性腺激素)治疗的不孕患者的观察。
Fertil Steril. 1978 May;29(5):492-5.

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