Ben-Rafael Z, Matalon A, Blankstein J, Serr D M, Lunenfeld B, Mashiach S
Fertil Steril. 1986 Jan;45(1):36-40. doi: 10.1016/s0015-0282(16)49093-x.
Two hundred fifty-six children were born in 195 births from 176 women that conceived after human menopausal gonadotropin/human chorionic gonadotropin (hMG/hCG)-induced ovulation. The secondary sex ratio was 50% male to 50% female births, which is not statistically different from the Israeli or Occidental population. The same trend was observed for single births and for twins. Thus, the data presented do not support the reports of increased numbers of female infants in those conceived after induction of ovulation. Factors that are expected to have been shown to affect sex ratio: maternal age at delivery, total number of ampules of hMG/hCG administered in the conceptional cycle, urinary estrogen levels on the day of hCG injection, degree of ovarian hyperstimulation syndrome, and time of insemination in relation to the basal body temperature rise were found to be insignificant. Thus, the hypothesis that a local hormonal environment (gonadotropin or estrogen levels) during hMG/hCG treatment possibly affects sex selection was not confirmed.
176名女性在接受人绝经期促性腺激素/人绒毛膜促性腺激素(hMG/hCG)诱导排卵后怀孕,共分娩195次,产下256名婴儿。第二性比为男婴与女婴各占50%,与以色列或西方人群无统计学差异。单胎和双胎情况也呈现相同趋势。因此,本文所呈现的数据并不支持有关诱导排卵后受孕所生女性婴儿数量增加的报道。预期已被证明会影响性比的因素:分娩时的母亲年龄、受孕周期中注射hMG/hCG的安瓿总数、注射hCG当天的尿雌激素水平、卵巢过度刺激综合征的程度以及与基础体温上升相关的授精时间,均无显著意义。因此,关于hMG/hCG治疗期间局部激素环境(促性腺激素或雌激素水平)可能影响性别选择的假设未得到证实。