Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.
Occup Environ Med. 2019 Apr;76(4):201-207. doi: 10.1136/oemed-2018-105333. Epub 2019 Feb 25.
There is limited evidence from longitudinal studies on transportation noise from different sources and development of ischaemic heart disease (IHD) and stroke.
This cohort study assessed associations between exposure to noise from road traffic, railway or aircraft and incidence of IHD and stroke.
In a cohort of 20 012 individuals from Stockholm County, we estimated long-term residential exposure to road traffic, railway and aircraft noise. National Patient and Cause-of-Death Registers were used to identify IHD and stroke events. Information on risk factors was obtained from questionnaires and registers. Adjusted HR for cardiovascular outcomes related to source-specific noise exposure were computed using Cox proportional hazards regression.
No clear or consistent associations were observed between transportation noise and incidence of IHD or stroke. However, noise exposure from road traffic and aircraft was related to IHD incidence in women, with HR of 1.11 (95% CI 1.00 to 1.22) and 1.25 (95% CI 1.09 to 1.44) per 10 dB L, respectively. For both sexes taken together, we observed a particularly high risk of IHD in those exposed to all three transportation noise sources at≥45 dB L, with a HR of 1.57 (95% CI 1.06 to 2.32), and a similar tendency for stroke (HR 1.42; 95% CI 0.87 to 2.32).
No overall associations were observed between transportation noise exposure and incidence of IHD or stroke. However, there appeared to be an increased risk of IHD in women exposed to road traffic or aircraft noise as well as in those exposed to multiple sources of transportation noise.
从不同来源的交通噪声的纵向研究和缺血性心脏病(IHD)和中风的发展来看,证据有限。
本队列研究评估了道路交通、铁路和飞机噪声暴露与 IHD 和中风发病的关系。
在斯德哥尔摩县的 20012 名个体的队列中,我们估计了长期居住的道路交通、铁路和飞机噪声暴露情况。利用国家患者和死因登记处来识别 IHD 和中风事件。利用问卷和登记处来获取有关风险因素的信息。使用 Cox 比例风险回归计算与特定来源噪声暴露相关的心血管结局的调整 HR。
未观察到交通噪声与 IHD 或中风发病之间存在明显或一致的关联。然而,道路交通和飞机噪声暴露与女性的 IHD 发病有关,每增加 10dB L,其 HR 分别为 1.11(95%CI 1.00 至 1.22)和 1.25(95%CI 1.09 至 1.44)。对于男女两性合并,我们观察到暴露于≥45dB L 的所有三种交通噪声源的个体发生 IHD 的风险特别高,HR 为 1.57(95%CI 1.06 至 2.32),且中风也存在类似的趋势(HR 1.42;95%CI 0.87 至 2.32)。
未观察到交通噪声暴露与 IHD 或中风发病之间存在总体关联。然而,女性暴露于道路交通或飞机噪声以及暴露于多种交通噪声源的个体似乎存在 IHD 风险增加的趋势。