Naqvi Atta Abbas, Hassali Mohamed Azmi, Aftab Muhammad Tariq, Nadir Muhammad Nehal
Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, University Sains Malaysia (USM), Penang, Malaysia.
Department of Pharmacology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
J Pak Med Assoc. 2019 Feb;69(2):216-223.
The study aimed to perceived barriers to medication adherence in patients with chronic illnesses..
A qualitative study was conducted in a tertiary care hospital in Karachi in September 2017, using grounded theory and inductive approach. Interviews were conducted using a checklist in Urdu language from patients of chronic illnesses determined based on medicines dispensed from the out-patient pharmacy in hospital. Interviews were recorded, transcribed verbatim, translated in English and validated. The translated quotations were analysed using a qualitative analysis software, and thematic analysis was conducted. Codes were generated and analysed by semantic linkages and network analysis using ATLAS.ti qualitative research software.
Of the 16 patients interviewed, 8(50%) were males and 8(50%) were females. Barriers to medication adherence identified were patient behaviour (intentional and un-intentional non-adherence), comorbidity and pill burden, cost-related non-adherence, and low patient knowledge. The last barrier was associated with the rest.
Counselling has the potential to increase patient knowledge regarding medication use, and active pharmacist-physician collaboration can improve medication adherence..
本研究旨在了解慢性病患者在药物依从性方面所面临的障碍。
2017年9月，在卡拉奇的一家三级护理医院进行了一项定性研究，采用扎根理论和归纳法。使用乌尔都语清单对根据医院门诊药房配药确定的慢性病患者进行访谈。访谈进行了录音，逐字转录，翻译成英文并进行了验证。使用定性分析软件对翻译后的引述进行分析，并进行了主题分析。使用ATLAS.ti定性研究软件通过语义联系和网络分析生成并分析代码。
在接受访谈的16名患者中，8名（50%）为男性，8名（50%）为女性。确定的药物依从性障碍包括患者行为（有意和无意的不依从）、合并症和药丸负担、与费用相关的不依从以及患者知识水平低。最后一个障碍与其他障碍相关。
咨询有可能增加患者对药物使用的了解，积极的药剂师与医生合作可以提高药物依从性。
