Ajaezi Godwin Chukwuebuka, Amadi Cecilia Nwadiuto, Ekhator Osazuwa Clinton, Igbiri Sorbari, Orisakwe Orish Ebere
Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Rivers State, Nigeria (G.C.A.).
Toxicology Unit, Faculty of Pharmacy, University of Port Harcourt, Rivers State, Nigeria (C.N.A., O.C.E., S.I., O.E.O.).
J Cosmet Sci. 2018 Nov/Dec;69(6):429-445.
Twenty different brands of cosmetic products were purchased from supermarkets in Port Harcourt, Rivers State, Nigeria, with the aims to determine the levels of metals and assess the health risk to humans through long-term usage. The concentration of metals (arsenic, lead, mercury, cadmium, and nickel) in the cosmetic samples was measured with atomic absorption spectrophotometry after acid digestion. The concentration of metals in these brands of cosmetic studied ranged from As: 0.001-0.0161 mg/kg, Pb: 0.289-2.873 mg/kg, Hg: 0.001-0.0014 mg/kg, Cd: 0.001-0.334 mg/kg, and Ni: 0.007-2.748 mg/kg. The metal and metalloid contents were less than the regulatory limits set for both metal impurities and as color additives. The target hazard quotient, hazard index, and cancer risk were less than the acceptable limit, indicating a measure of safety. Cosmetics sold in Nigeria may not add to the body burden of metals and metalloids.
从尼日利亚河流州哈科特港的超市购买了20个不同品牌的化妆品，目的是测定金属含量，并评估长期使用对人体的健康风险。酸消解后，用原子吸收分光光度法测量化妆品样品中金属（砷、铅、汞、镉和镍）的浓度。所研究的这些品牌化妆品中的金属浓度范围为：砷：0.001 - 0.0161毫克/千克，铅：0.289 - 2.873毫克/千克，汞：0.001 - 0.0014毫克/千克，镉：0.001 - 0.334毫克/千克，镍：0.007 - 2.748毫克/千克。金属和类金属含量低于针对金属杂质和作为色素添加剂所设定的监管限值。目标危害商数、危害指数和癌症风险均低于可接受限值，表明具有一定的安全性。在尼日利亚销售的化妆品可能不会增加人体中金属和类金属的负担。
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