Department of Experimental Pharmacology & Toxicology, Faculty of Pharmacy, University of Port-Harcourt, Port Harcourt, Rivers State, Nigeria.
Department of Experimental Pharmacology & Toxicology, Faculty of Pharmacy, Madonna University, Elele, Rivers State, Nigeria.
Environ Sci Pollut Res Int. 2019 Jan;26(2):1921-1931. doi: 10.1007/s11356-018-3706-3. Epub 2018 Nov 20.
The affordability of candies and chocolates makes their consumption common especially in children. Heavy metal contamination of these candies is well known. This study has estimated health risks associated with heavy metals (HM; Pb, Cd, Cr, Ni, and Zn) in commonly consumed candies in Nigeria. Fifty candies/sweets and chocolates/chewing gums bought from different stores in Port Harcourt and Uyo in Niger Delta, Nigeria, were processed and digested in perchloric acid. The filtrate was analyzed for these heavy metals using atomic absorption spectroscopy (AAS). Pb/Zn and Cd/Zn ratios were calculated. Daily intake, the target hazard quotient (THQ), the hazard index (HI), and the cancer risk were estimated for children. About 80% of the samples exceeded the 0.1 mg/kg permissible lead level in candies. Milk sweet had the highest Pb:Zn and Cd:Zn ratios of 0.99 and 0.40 respectively. For chocolates, the Emperor had the highest Pb:Zn (0.50) ratios and Trident had the highest Cd:Zn (0.57) ratios. The calculated percentage provisional tolerable weekly intake (%PTWI) of cadmium from consumption of chocolates and candies was higher than the Joint Expert Committee for Food Additives (JECFA) standard, and the cancer risk of lead, cadmium, and chromium ranged between 10 and 10. Consumption of some candies by children in Nigeria may pose significant health risks.
糖果和巧克力的价格实惠,使得它们的消费非常普遍,尤其是在儿童中。这些糖果中的重金属污染是众所周知的。本研究估计了尼日利亚常见糖果中重金属(Pb、Cd、Cr、Ni 和 Zn)带来的健康风险。从尼日利亚尼日尔三角洲的哈科特港和乌约的不同商店购买了 50 颗糖果/甜食和巧克力/口香糖,并在高氯酸中进行处理和消化。使用原子吸收光谱法(AAS)分析滤液中的这些重金属。计算了 Pb/Zn 和 Cd/Zn 比值。估计了儿童的每日摄入量、目标危害系数(THQ)、危害指数(HI)和癌症风险。大约 80%的样品中糖果的铅含量超过了 0.1mg/kg 的允许水平。牛奶糖的 Pb:Zn 和 Cd:Zn 比值最高,分别为 0.99 和 0.40。对于巧克力,皇帝巧克力的 Pb:Zn 比值最高(0.50),而 Trident 巧克力的 Cd:Zn 比值最高(0.57)。巧克力和糖果中镉的暂定每周可耐受摄入量(%PTWI)的计算值高于食品添加剂联合专家委员会(JECFA)标准,铅、镉和铬的癌症风险在 10 到 10 之间。尼日利亚儿童食用某些糖果可能会带来重大健康风险。