1 Graduate Program in Biomedical Gerontology, School of Medicine, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
2 Laboratory of Biochemistry and Molecular Genetics, Institute of Geriatrics and Gerontology, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Metab Syndr Relat Disord. 2019 May;17(4):232-239. doi: 10.1089/met.2018.0113. Epub 2019 Feb 26.
Studies have demonstrated the relevance of anthropometric indicators in the prediction of metabolic syndrome (MetS). However, researches involving older people are still scarce. Therefore, the objective was to describe the frequency of MetS and to determine the performance of anthropometric indicators as predictors of MetS in the total sample, in men and women. Cross-sectional study involving 479 elderly individuals attended in primary health care. The revised (NCEP-ATPIII) guidelines were used for the MetS diagnosis. The anthropometric indicators evaluated were neck circumference, sagittal abdominal diameter (SAD), SAD/height, sagittal index, and conicity index (C-Index). The predictive performance of the MetS anthropometric indicators was determined using a receiver operating characteristic (ROC) curve. A cutoff point >0.700 was used to evaluate diagnostic performance. The frequency of MetS was 60.5%. The anthropometric indicators demonstrating adequate performance were in total sample: SAD/height (auROC = 0.810), SAD (auROC = 0.777), and C-Index (auROC = 0.706); in women: SAD (auROC = 0.820), SAD/height (auROC = 0.810), neck circumference (auROC = 0.782), and C-Index (auROC = 0.727); in men: SAD/height (auROC = 0.768), SAD (auROC = 0.760), and C-Index (auROC = 0.724). A high frequency of MetS was observed. Of the five anthropometric indicators investigated, three presented good performance in the total sample (SAD, SAD/height, and C-Index), four in women (SAD, SAD/height, neck circumference, and C-Index), and three in men (SAD, SAD/height, and C-Index). The anthropometric indicators, SAD, SAD/height, and C-Index, proved to perform adequately in all the three segments investigated.
研究表明,人体测量指标与代谢综合征(MetS)的发生密切相关。然而,目前涉及老年人的研究仍然较少。因此,本研究的目的是描述老年人代谢综合征的发生率,并确定人体测量指标作为预测代谢综合征的指标在总样本、男性和女性中的表现。
这是一项涉及在初级保健中就诊的 479 名老年人的横断面研究。采用修订后的(NCEP-ATPIII)指南进行代谢综合征的诊断。评估的人体测量指标包括颈围、矢状腹部直径(SAD)、SAD/身高、矢状指数和锥度指数(C-Index)。采用受试者工作特征(ROC)曲线来确定代谢综合征人体测量指标的预测性能。使用截点>0.700 来评估诊断性能。
代谢综合征的发生率为 60.5%。在总样本中,表现出良好性能的人体测量指标有 SAD/身高(auROC=0.810)、SAD(auROC=0.777)和 C-Index(auROC=0.706);在女性中,表现出良好性能的人体测量指标有 SAD(auROC=0.820)、SAD/身高(auROC=0.810)、颈围(auROC=0.782)和 C-Index(auROC=0.727);在男性中,表现出良好性能的人体测量指标有 SAD/身高(auROC=0.768)、SAD(auROC=0.760)和 C-Index(auROC=0.724)。
观察到代谢综合征的发生率较高。在所研究的五个人体测量指标中,有三个在总样本中表现出良好性能(SAD、SAD/身高和 C-Index),四个在女性中表现出良好性能(SAD、SAD/身高、颈围和 C-Index),三个在男性中表现出良好性能(SAD、SAD/身高和 C-Index)。SAD、SAD/身高和 C-Index 这三个人体测量指标在所有三个研究组段均表现出良好性能。