Fischer P, Boldt I, Petrasch K, Franken T
Strahlenther Onkol. 1986 Jan;162(1):1-7.
The authors present the results of primary radiotherapy in 73 patients with esophagus carcinomas. A subgroup of non-circular squamous-cell carcinomas without remote and lymph node metastases (n = 19) shows a prognosis which is very favorable for this tumor. As local therapy of the esophagus carcinoma can only aim at a tolerable course of the disease until the appearance of metastases, the results achieved give occasion to doubt the priority of surgery in case of operable tumors. The question arises if primary radiotherapy wouldn't be an effective and not very risky alternative for patients presenting these favorable criteria.
作者展示了73例食管癌患者接受原发性放射治疗的结果。一组无远处及淋巴结转移的非圆形鳞状细胞癌亚组(n = 19)显示出对该肿瘤非常有利的预后。由于食管癌的局部治疗只能旨在使疾病在出现转移之前有一个可耐受的病程,所取得的结果让人怀疑在可手术肿瘤的情况下手术的优先性。问题是对于符合这些有利标准的患者,原发性放射治疗是否不是一种有效且风险不大的替代方案。