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追踪裂谷热疫情:2016 年,从马里到欧洲和其他国家。

Tracking Rift Valley fever: From Mali to Europe and other countries, 2016.

机构信息

French Armed Forces Centre for Epidemiology and Public Health (CESPA), Marseille, France.

Laveran Military Teaching Hospital, Marseille, France.

出版信息

Euro Surveill. 2019 Feb;24(8). doi: 10.2807/1560-7917.ES.2019.24.8.1800213.

DOI:10.2807/1560-7917.ES.2019.24.8.1800213
PMID:30808441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6446957/
Abstract

On 16 September 2016, the World Health Organization confirmed a Rift Valley fever (RVF) outbreak in Niger. Epidemiological surveillance was reinforced among the French Armed Forces deployed in Niger and bordering countries: Chad, Mali and Burkina Faso. On 26 October, a probable case of RVF was reported in a service member sampled in Mali 3 weeks earlier. At the time the result was reported, the patient was on vacation on Martinique. An epidemiological investigation was conducted to confirm this case and identify other cases. Finally, the case was not confirmed, but three suspected cases of RVF were confirmed using serological and molecular testing. RVF viral RNA was detectable in whole blood for 57 and 67 days after onset of symptoms for two cases, although it was absent from plasma and serum. At the time of diagnosis, these cases had already returned from Mali to Europe. The infectivity of other arboviruses in whole blood has already been highlighted. That RVF virus has been detected in whole blood that long after the onset of symptoms (67 days) raises the question of its potential prolonged infectivity. Because of exposure to tropical infectious diseases during deployment, military populations could import emerging pathogens to Europe.

摘要

2016 年 9 月 16 日,世界卫生组织确认尼日尔爆发裂谷热(RVF)疫情。法国在尼日尔和邻国乍得、马里和布基纳法索部署的武装部队加强了流行病学监测。10 月 26 日,在马里 3 周前采样的一名服务成员报告了一例可能的 RVF 病例。报告结果时,该患者正在马提尼克岛度假。开展了一项流行病学调查以确认该病例并确定其他病例。最终,该病例未得到确认,但使用血清学和分子检测确认了三例 RVF 疑似病例。两名病例的症状发作后 57 天和 67 天,全血中可检测到 RVF 病毒 RNA,尽管血浆和血清中未检测到。在诊断时,这些病例已经从马里返回欧洲。全血中其他虫媒病毒的传染性已经得到强调。RVF 病毒在症状发作后(67 天)如此长时间内仍可检测到,这引发了其潜在延长传染性的问题。由于在部署期间接触热带传染病,军事人员可能会将新出现的病原体输入欧洲。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/080f/6446957/3101bdd226d9/1800213-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/080f/6446957/3101bdd226d9/1800213-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/080f/6446957/3101bdd226d9/1800213-f1.jpg

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