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2018 年 2 月至 4 月,英国和澳大利亚耐头孢曲松和高水平阿奇霉素耐药病例的遗传相关性。

Genetic relatedness of ceftriaxone-resistant and high-level azithromycin resistant cases, United Kingdom and Australia, February to April 2018.

机构信息

Forensic and Scientific Services, Queensland Department of Health, Brisbane, Queensland, Australia.

The University of Queensland, Brisbane, Queensland, Australia.

出版信息

Euro Surveill. 2019 Feb;24(8). doi: 10.2807/1560-7917.ES.2019.24.8.1900118.

DOI:10.2807/1560-7917.ES.2019.24.8.1900118
PMID:30808445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6446956/
Abstract

Between February and April 2018, three ceftriaxone-resistant and high-level azithromycin-resistant cases were identified; one in the United Kingdom and two in Australia. Whole genome sequencing was used to show that the isolates from these cases belong to a single gonococcal clone, which we name the A2543 clone.

摘要

在 2018 年 2 月至 4 月期间,鉴定出三例头孢曲松耐药且高水平耐阿奇霉素的病例;一例在英国,两例在澳大利亚。全基因组测序显示,这些病例的分离株属于单一淋球菌克隆,我们将其命名为 A2543 克隆。

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本文引用的文献

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Emerg Infect Dis. 2018 Aug;24(8):1573-1575. doi: 10.3201/eid2408.180295.
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Gonorrhoea treatment failure caused by a strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.2018 年 2 月,英国出现一株同时对头孢曲松和高水平阿奇霉素耐药的淋病奈瑟菌株导致治疗失败。
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Genetic characterisation of Neisseria gonorrhoeae resistant to both ceftriaxone and azithromycin.
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Local emergence and global evolution of with high-level resistance to azithromycin.对阿奇霉素具有高水平耐药性的[具体对象未明确,可能是某种病原体等]的局部出现和全球演变 。
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