Department of Translational Medicine, Division of Urological Cancers, Lund University, and the Department of Urology, Skåne University Hospital, Malmö, Sweden.
Clin Cancer Res. 2019 May 1;25(9):2679-2681. doi: 10.1158/1078-0432.CCR-19-0061. Epub 2019 Feb 26.
/ prostate cancer is an aggressive disease with poor clinical outcome. New data suggest a novel treatment by upregulating the expression of miR-338-5p/-421 through epigenetic modulation or by miRNA replacement. This is a new and interesting concept that warrants further exploration in clinical trials..
前列腺癌是一种侵袭性疾病，临床预后较差。新数据表明，通过表观遗传调节或 miRNA 替代来上调 miR-338-5p/-421 的表达是一种新颖而有趣的治疗方法。这是一个值得在临床试验中进一步探索的新概念。
