Zasukhina G D, Barashnev Iu I, L'vova G N, Sinel'shchikova T A, Shoniia N N
Biull Eksp Biol Med. 1986 Feb;101(2):195-7.
Repair processes in blood lymphocytes of children with hereditary homocystinuria have been studied. The identical results on the defective repair processes of damaged DNA were received by the two methods used. The method of vaccinia virus reactivation registered total disturbance of the repair function in cells, while the method of alkaline elution revealed the defects in the enzymes providing resynthesis of DNA breaks in normal conditions.
对患有遗传性高胱氨酸尿症儿童的血液淋巴细胞中的修复过程进行了研究。使用的两种方法在受损DNA修复过程缺陷方面得到了相同的结果。痘苗病毒复活法显示细胞修复功能完全紊乱，而碱性洗脱法揭示了在正常情况下负责DNA断裂再合成的酶存在缺陷。
