Stoop A, de Boo T, Lemmens W, Folgering H
Respiration. 1986;49(1):37-44. doi: 10.1159/000194857.
In 303 subjects, amongst whom 250 patients suspected of suffering from the hyperventilation syndrome, lung functions were measured, a hyperventilation provocation test was performed and a questionnaire was taken. The subjects were subdivided into categories of nonhyperventilators, and 3 categories of hyperventilators, on the basis of objective measurable lung function parameters and the result of the provocation test. The outcome of the questionnaire in the various categories was evaluated. Some subjective complaints were related to age, sex, PaCO2 and lung function of the subjects. There was no clear correlation between PaCO2 and neurological signs. Hypoventilation after the provocation test occurred in only 5 subjects. No indications were found that hyperventilation might be an early sign of chronic obstructive lung disease.
在303名受试者中，其中250名疑似患有过度换气综合征的患者，进行了肺功能测量、过度换气激发试验并填写了问卷。根据客观可测量的肺功能参数和激发试验结果，将受试者分为非过度换气者类别以及3类过度换气者。对各类别的问卷结果进行了评估。一些主观症状与受试者的年龄、性别、动脉血二氧化碳分压（PaCO2）和肺功能有关。PaCO2与神经体征之间没有明显的相关性。激发试验后仅有5名受试者出现通气不足。未发现有迹象表明过度换气可能是慢性阻塞性肺疾病的早期迹象。
