Peiffer Claudine
Dyspnea Clinic, Department of Physiology, University Children Hospital Robert Debré (AP-HP), Paris, France.
Front Neurosci. 2023 Oct 9;17:1270556. doi: 10.3389/fnins.2023.1270556. eCollection 2023.
There is currently growing clinical concern regarding dysfunctional breathing disorder(s) (DBD), an umbrella term for a set of multidimensional clinical conditions that are characterized by altered breathing pattern associated with a variety of intermittent or chronic symptoms, notably dyspnea, in the absence or in excess of, organic disease. However, several aspects of DBD remain poorly understood and/or open to debate, especially the inconsistent relationship between the array of experienced symptoms and their supposedly underlying mechanisms. This may be partly due to a more general problem, i.e., the prevailing way we conceptualize symptoms. In the present article, after a brief review of the different aspects of DBD from the current perspective, I submit a call for considering DBD under the innovating perspective of the Bayesian brain hypothesis, i.e., a potent and novel model that fundamentally changes our views on symptom perception.
目前,临床上对功能失调性呼吸障碍(DBD)的关注日益增加,DBD是一组多维度临床病症的统称,其特征是呼吸模式改变,伴有各种间歇性或慢性症状,尤其是呼吸困难,无论是否存在器质性疾病。然而,DBD的几个方面仍知之甚少和/或存在争议,特别是所经历症状的一系列表现与其潜在机制之间的不一致关系。这可能部分归因于一个更普遍的问题,即我们对症状的概念化方式。在本文中,在从当前角度简要回顾DBD的不同方面之后,我呼吁从贝叶斯大脑假说这一创新角度来考虑DBD,这是一个强大且新颖的模型,从根本上改变了我们对症状感知的看法。